Heart Stand Setup
Heart Stand Setup - Related Videos
09:32
Standing Waves
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2023
Source: Arianna Brown, Asantha Cooray, PhD, Department of Physics & Astronomy, School of Physical Sciences, University of California, Irvine, CA Standing waves, or stationary waves, are waves that appear not to propagate and are produced by the interference of two waves traveling in opposite directions with the same frequency and amplitude. These waves appear to vibrate up and down with no linear movement and are most easily identified in vibrating finite media like a plucked guitar string,...
01:17
Standing Waves
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2023
Sometimes waves do not seem to move; rather, they just vibrate in place. Unmoving waves can be seen on the surface of a glass of milk kept in a refrigerator, which is one example of standing waves. Vibrations from the refrigerator motor create waves on the milk that oscillate up and down but do not seem to move across the surface. These waves are formed or created by the superposition of two or more identical moving waves in opposite directions. The waves move through each other, with their...
07:27
Implantation of Total Artificial Heart in Congenital Heart Disease
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Cited by 40 •
2014
This is a case report of a patient with congenitally corrected transposition of the great arteries (CCTGA) who received a total artificial heart (TAH) as a bridge to heart transplant. The TAH was successfully implanted with modifications to accommodate the patient's congenitally malformed heart.
01:15
Standing Electromagnetic Waves
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2023
Electromagnetic waves can be reflected; the surface of a conductor or a dielectric can act as a reflector. As electric and magnetic fields obey the superposition principle, so do electromagnetic waves. The superposition of an incident wave and a reflected electromagnetic wave produces a standing wave analogous to the standing waves created on a stretched string. Suppose a sheet of a perfect conductor is placed in the yz-plane, and a linearly polarized electromagnetic wave traveling in the...
01:28
Standing Waves in a Cavity
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2023
A household microwave and lasers are examples of standing electromagnetic waves in a cavity. When two conducting metal plates are placed parallel at the nodal planes, it creates a cavity where standing waves are formed. The cavity between the two planes is analogous to a stretched string held at the points x = 0 and x = L. Here, the distance 'L' between the two planes must be an integer multiple of half of the wavelength. The wavelengths that satisfy this condition are given by: The...
FAQs
Mounting the isolated heart on a cannula through the aorta allows the perfusion solution to enter the route that supplies the coronary circulation. Researchers can therefore regulate delivery pressure while the heart remains active. This arrangement makes coronary perfusion a controlled experimental variable, helping link altered conditions to changes in cardiac performance.
The oxygenated nutrient solution supplies the isolated tissue with the conditions needed to preserve physiological activity during the experiment. Its delivery through the perfusion circuit supports continued beating and allows investigators to study responses under controlled laboratory conditions. This controlled supply enables measurements of rate, force, and coronary flow to be interpreted as features of an active preparation.
Controlled perfusion pressure gives investigators a defined condition for examining how the heart responds. Because delivery through the aortic cannula can be maintained under laboratory control, measurements such as coronary flow and contractile force can be compared across experimental conditions. The setup therefore helps distinguish responses associated with controlled pressure changes from influences present in an intact animal.
Depending on the experimental design, investigators can monitor cardiac rate, contractile force, and coronary flow. These readouts describe different aspects of the preparation: beating frequency, mechanical performance, and circulation through the coronary vessels. Recording them together helps researchers determine whether a drug or altered condition affects rate, contraction, perfusion, or more than one feature.
The main workflow begins by supporting the isolated heart and mounting it on a cannula through the aorta. Researchers then deliver oxygenated nutrient solution through the system while maintaining controlled pressure. During perfusion, they observe the continuing preparation and record selected outcomes such as cardiac rate, contractile force, and coronary flow.
This preparation is useful when researchers need to examine cardiac behavior without influences from the intact animal. It supports cardiovascular physiology studies, drug-response experiments in pharmacology, and experimental disease research. By keeping perfusion conditions controlled, investigators can focus on how a treatment or changed environment affects measurable heart function in an ex vivo system.