Light Treatment
Light Treatment - Related Videos
05:09
A Riboflavin and UV Light Treatment of Platelet Products to Eliminate Bacteria
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2025
This video demonstrates the riboflavin and UV light-based pathogen reduction process against high-titer bacterial contamination in human platelet products. This process could help to lower the risk of severe adverse transfusion events associated with bacterial contamination.
02:59
Light-Activated Treatment of Bacterial Biofilms Using a Photosensitizer Precursor
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2026
Source: Zhao, K., et al. An In Vitro Model to Study the Effect of 5-Aminolevulinic Acid-mediated Photodynamic Therapy on Staphylococcus aureus Biofilm. J. Vis. Exp. (2018)The video demonstrates a photodynamic therapy protocol to assess antibacterial effects on Gram-positive bacterial biofilms. Biofilms are divided into four groups: two receive a photosensitizer precursor, and two receive a buffer. All are incubated in the dark, followed by red light exposure to one precursor-treated group and...
10:32
Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination
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Cited by 19 •
2015
The storage conditions of platelet products create an ideal environment for bacterial contaminants to multiply to dangerous levels. The goal of this study was to use a colony forming assay to evaluate a riboflavin based pathogen reduction process against high titer bacterial contamination in human platelet products.
05:00
Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
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Cited by 41 •
2019
Dry eye disease is an increasingly common condition, which strongly impair patients' life quality. Recently, a new device employing intense pulsed light, specifically designed for the periocular area, has been shown to improve tear film stability and ocular discomfort symptoms in dry eye disease owing to meibomian gland dysfunction.
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Cited by 26 •
2013
Psoriasis is a chronic, immune-mediated inflammatory skin disease. The Goeckerman regimen, formulated for the treatment of psoriasis, consists of exposure to ultraviolet B (UVB) light and application of crude coal tar (CCT). The following protocol is for the administration of Goeckerman therapy for the treatment of moderate-to-severe psoriasis.
FAQs
Wavelength determines which molecules or photoreceptors can absorb the radiation and therefore which biological pathways may respond. Visible, ultraviolet, and infrared light can produce different effects because their energy interacts with different cellular targets. This selectivity helps researchers connect a particular light exposure with changes in cellular signaling, gene expression, metabolism, or DNA structure.
Intensity and exposure time together influence the amount of radiation delivered to a biological system. A controlled dose can reveal stimulation or regulated responses, whereas excessive exposure may produce damage. Researchers therefore adjust these variables deliberately and record them carefully so that changes in cells, tissues, or organisms can be interpreted as responses to the treatment rather than uncontrolled exposure.
After absorption by a molecule or photoreceptor, light energy can alter downstream cellular processes. These changes may affect signaling pathways, gene expression, metabolism, or the structure of DNA. Measuring the resulting biological response allows investigators to study how organisms convert environmental light into molecular and cellular changes, linking the initial exposure to a measurable outcome.
A sound procedure controls the radiation type, wavelength, intensity, and exposure time, while also specifying the biological material being tested. These parameters establish the treatment dose and make comparisons between experimental conditions possible. Careful control is especially important when the goal is to distinguish a useful biological response from light-induced damage.
Its applications include investigations of photosynthesis, circadian rhythms, microbial growth, cell behavior, and tissue responses. Each use examines a different relationship between radiation and biology, from environmental sensing to changes in cellular activity. Findings can support photobiology research, therapeutic development, and biotechnology by showing how controlled light exposure influences living systems.
These experiments can reveal how organisms sense and respond to physical conditions in their environment. Depending on the system, researchers may track changes in metabolism, gene expression, cellular signaling, growth, behavior, or tissue response. In biology, such observations connect light exposure with broader organismal functions and help evaluate whether a response reflects stimulation or damage.