Musculoskeletal Tissue
Musculoskeletal Tissue - Related Videos
07:49
Isolating Stem Cells from Soft Musculoskeletal Tissues
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Cited by 21 •
2010
Isolating adult stem cells from musculoskeletal soft tissues based on the cell's adherence speed to flask.
10:53
A Novel Application of Musculoskeletal Ultrasound Imaging
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Cited by 14 •
2013
We describe a new ultrasound-based vector tissue Doppler imaging technique to measure muscle contraction velocity, strain and strain rate with sub-millisecond temporal resolution during dynamic activities. This approach provides complementary measurements of dynamic muscle function and could lead to a better understanding of mechanisms underlying musculoskeletal disorders.
08:52
3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue
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Cited by 34 •
2017
3D ultrasound imaging (3DUS) allows fast and cost-effective morphometry of musculoskeletal tissues. We present a protocol to measure muscle volume and fascicle length using 3DUS.
09:53
Volumetric Imaging and Analysis of Primary Cilia in Musculoskeletal Tissue using the ARL13B-CENTRIN-2 Mouse Model
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Cited by 1 •
2025
This method describes the exploitation of the endogenous signal in an ARL13B-CENTRIN-2 transgenic mouse model to image primary cilia in situ, in three dimensions across large areas of mineralized tissue, from tissue collection to analysis of cilia organization. This protocol may also be applied to other types of tissues.
09:32
Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
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Cited by 3 •
2018
During landing, lower-body bones experience large mechanical loads and are deformed. It is essential to measure bone deformation to better understand the mechanisms of bone stress injuries associated with impacts. A novel approach integrating subject-specific musculoskeletal modeling and finite element analysis is used to measure tibial strain during dynamic movements.
FAQs
Bone remodeling is a continuous balancing process involving osteoblasts and osteoclasts. Their coordinated activity allows bone tissue to be renewed rather than remaining structurally unchanged. This dynamic behavior is important for understanding how bones maintain support and why remodeling becomes a major focus in biological research on osteoporosis and tissue-engineering strategies.
Actin and myosin provide the contractile machinery within skeletal muscle fibers. Their filament interaction produces force that can be transmitted through the muscle and associated connective tissues to contribute to movement. Studying this mechanism helps biology researchers connect events at the fiber level with whole-body motion and the effects of exercise.
Cartilage and connective tissues help distribute mechanical loads and stabilize joints during movement. By contributing to how forces are handled across the musculoskeletal system, these tissues support coordinated motion rather than isolated action by muscle or bone. Their roles make them important subjects in research on arthritis, biomechanics, and injury repair.
Musculoskeletal function depends on cooperation among tissues with different mechanical roles. Skeletal muscle generates force, bone provides a rigid supporting framework, and cartilage, tendons, ligaments, and related connective tissues help transmit forces, distribute loads, or stabilize joints. Viewing these components as an interconnected system is essential for interpreting movement, protection, and tissue injury.
Its organization connects biological structure with mechanical function and clinical outcomes. Biology examines tissue development and cellular activity, biomechanics considers support and movement, and medicine addresses conditions or damage affecting the system. This cross-disciplinary perspective supports research into exercise, osteoporosis, arthritis, injury repair, and strategies for engineering replacement or repaired tissues.
Research on musculoskeletal tissue can investigate normal development, responses to exercise, and changes associated with injury or disease. It also provides a foundation for studying osteoporosis and arthritis, while tissue-engineering strategies seek ways to address damaged or insufficient tissues. These applications link basic tissue mechanisms with broader goals in repair and health research.