Near Infrared Light
Near Infrared Light - Related Videos
02:29
Modulating Sensory Neuronal Signaling in a Mouse Model Using Near Infrared Light
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2025
Source: Zhang, L., et al. Near Infrared (NIr) Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium. J. Vis. Exp. (2015)This video demonstrates the process of applying NIr light to a shaved mouse scalp to activate vestibular neurons and stimulate superoxide dismutase-1 (SOD-1) production, supporting neuronal function. The procedure highlights NIr therapy as a neuroprotective strategy.
06:56
Near Infrared (NIr) Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium
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Cited by 4 •
2015
Mitochondrial dysfunction is a hallmark of cellular senescence. This paper uses non-invasive near-infrared (NIr) treatment to improve mitochondrial function in the aging mouse vestibular sensory epithelium.
10:26
Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light
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Cited by 1 •
2017
A protocol for the fabrication of plastic microfluidic devices with transparent view-ports for visible and infrared light imaging is described.
09:23
Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods
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2025
This protocol presents techniques and methodology necessary for targeted hyperthermic therapy in solid tumor models. The approach leverages the photothermal conversion of near-infrared light by intratumorally injected gold nanorods to induce localized heating within the tumor microenvironment.
08:11
Infrared Spectroscopy
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2023
Source: Vy M. Dong and Zhiwei Chen, Department of Chemistry, University of California, Irvine, CA This experiment will demonstrate the use of infrared (IR) spectroscopy (also known as vibrational spectroscopy) to elucidate the identity of an unknown compound by identifying the functional group(s) present. IR spectra will be obtained on an IR spectrometer using the attenuated total reflection (ATR) sampling technique with a neat sample of the unknown.
FAQs
Chromophores determine how tissue absorbs near-infrared photons. Hemoglobin, water, and lipids each contribute wavelength-dependent absorption, while surrounding tissue also scatters the light. The combined effects alter how much radiation is transmitted and what signal is detected, allowing measurements to reflect differences in tissue composition and physiological state.
Different wavelengths interact differently with tissue because absorption by hemoglobin, water, and lipids varies across the near-infrared range. These changes influence transmission and detected signals, so wavelength selection affects the biological information obtained. This principle helps distinguish measurements related to oxygenation, blood flow, or molecular composition.
Scattering redirects photons as they travel through tissue, changing their path before detection. Along with absorption, this process determines the strength and wavelength-dependent character of the transmitted signal. Accounting for both effects is important when interpreting near-infrared measurements, because the recorded signal reflects interactions throughout the tissue rather than a simple surface reading.
Near-infrared spectroscopy uses tissue-dependent changes in transmitted or detected light to assess biological properties noninvasively. Depending on the measurement, it can provide information about tissue oxygenation, blood flow, and molecular composition. These readouts make the technique useful for examining physiological conditions without requiring direct access to the measured tissue.
Near-infrared imaging uses wavelength-dependent interactions between light and tissue to generate signals related to biological composition and physiology. Absorption by hemoglobin, water, and lipids contributes to the measured contrast, while scattering influences photon transmission. Consequently, imaging can support assessment of tissue oxygenation, blood flow, and molecular composition in biological studies.
Controlled near-infrared exposure is studied as part of photobiomodulation, a research area focused on possible therapeutic effects of light. Control over exposure is important because the biological response is investigated under defined conditions rather than inferred from diagnostic measurements alone. This work extends near-infrared research from noninvasive assessment toward therapeutic applications.