Outer Root Sheath

The outer root sheath is an epithelial layer that surrounds the hair follicle and connects it with the epidermis, providing structural support and a reservoir of regenerative cells. During the hair cycle, stem and progenitor cells within the sheath respond to signals from the follicle niche, proliferate, and migrate to support follicle remodeling and hair production. Studying the outer root sheath helps clarify epithelial stem cell biology, tissue regeneration, and interactions between skin and hair follicles. This knowledge informs research on wound repair, hair loss, follicle development, and strategies for regenerative medicine.

Outer Root Sheath - Related Videos

Research

JoVE Journal - Medicine

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

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Cited by 4 •

2017

Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.

Research

JoVE Journal - Biology
Free Sample

Method for the Isolation of Francisella tularensis Outer Membranes

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Cited by 11 •

2010

A protocol for separating inner and outer membranes from Francisella tularensis by spheroplasting, osmotic lysis, and sucrose density gradient ultracentrifugation.

Time-lapse Fluorescence Imaging of Arabidopsis Root Growth with Rapid Manipulation of The Root Environment Using The RootChip

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Cited by 43 •

2012

This article provides a protocol for cultivation of Arabidopsis seedlings in the RootChip, a microfluidic imaging platform that combines automated control of growth conditions with microscopic root monitoring and FRET-based measurement of intracellular metabolite levels.

Separation of Inner and Outer Membrane Fractions of Gram-Negative Bacteria

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2025

Source: Cian, M. B. et. al., Separation of the Cell Envelope for Gram-negative Bacteria into Inner and Outer Membrane Fractions with Technical Adjustments for Acinetobacter baumannii. J. Vis. Exp. (2020)This video demonstrates the separation of the inner and outer membrane fractions of Gram-negative bacteria using sucrose gradient ultracentrifugation. The membrane fractions are purified and stored at low temperatures for targeted analysis of membrane-specific components.

Lateral Root Inducible System in Arabidopsis and Maize

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Cited by 8 •

2016

The Lateral Root Inducible System (LRIS) allows for synchronous induction of lateral roots and is presented for Arabidopsis thaliana and maize.

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