Personal Care Products
Personal Care Products - Related Videos
14:13
Detecting Estrogenic Ligands in Personal Care Products using a Yeast Estrogen Screen Optimized for the Undergraduate Teaching Laboratory
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Cited by 1 •
2018
This article presents an optimized yeast estrogen screen for quantifying ligands in Personal Care Products (PCPs) that bind estrogen receptors alpha (ERα) and/or beta (ERβ). The method incorporates two colorimetric substrate options, a six-day refrigerated incubation for use in undergraduate courses, and statistical tools for data analysis.
10:06
Personalized Needles for Microinjections in the Rodent Brain
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Cited by 3 •
2018
We describe here a protocol for microinjection in the rodent brain that uses quartz needles. These needles do not produce detectable tissue damage and ensure reliable delivery even in deep regions. Moreover, they can be adapted to research needs by personalized designs and can be re-used.
13:24
Basic Care Procedures
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2016
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN Mice and rats account for a large proportion of the animals used in biomedical research. Ensuring their welfare is both an ethical responsibility and essential for scientific validity. There are general procedures that apply to the majority of these mice and rats, but some of the animals, such as the immunocompromised ones, require additional steps to be taken to sustain them for...
08:29
Basic Mouse Care and Maintenance
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2023
Mice (Mus musculus) are small rodents that breed and sexually mature quickly, making them perfectly suited to generating large animal colonies for biological research. As compared to other mammalian species, mice are simple and inexpensive to maintain in the laboratory. Nevertheless, mouse colonies do have specific husbandry needs that are critical to preserving animal health and safety as well as experimental reproducibility. This video demonstrates standard practices that ensure mice are...
05:37
Proper Personal Protective Equipment
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2023
Robert M. Rioux & William A Elliott, Pennsylvania State University, University Park, PA Hazards are many and varied in the laboratory, but the right choice of PPE can make the laboratory a safe place to work.
FAQs
Surfactants remove oils during cleansing, which helps eliminate material from the body’s surface. Because the skin barrier depends partly on its surface composition, biological research examines whether this interaction alters barrier function or contributes to irritation. This makes surfactant selection important when designing products intended to cleanse effectively while limiting unwanted effects on living skin tissue.
Humectants attract water, so they contribute to the moisture-related effects of formulations applied to skin or hair. Their biological relevance comes from how added water may influence the condition and behavior of these tissues. Researchers therefore consider humectants when evaluating whether a product supports the desired surface properties without producing irritation or other adverse responses.
Preservatives limit microbial growth within a formulation, helping maintain product quality during use. However, biological evaluation also considers interactions with the resident microbiota, the microorganisms normally associated with skin. This distinction matters because controlling unwanted growth in a product and preserving compatibility with living tissues are related but separate concerns when selecting ingredients.
Evaluation commonly focuses on the skin barrier, hair structure, resident microbiota, and possible irritation or toxicity. These outcomes represent different dimensions of biological compatibility: barrier condition reflects skin function, structural analysis addresses hair, microbiota studies examine associated microorganisms, and irritation or toxicity testing considers harmful tissue responses. Together, they provide a broader assessment than appearance alone.
Researchers can compare formulations by examining which biological target each product is intended to influence and then assessing relevant outcomes. Cleansing products may be considered in relation to oils and the skin barrier, moisturizers in relation to water, and appearance-altering products in relation to skin or hair cells. This approach connects product purpose with measurable biological effects.
Biological evidence helps connect ingredient function with the responses of skin, hair, and associated microbiota. Studying surfactants, humectants, preservatives, and active compounds can reveal how formulations interact with living tissues, including possible irritation or toxicity. These findings support evidence-based ingredient selection, safer product design, and a clearer understanding of everyday chemical interactions with the body.