Silicone Membrane

A silicone membrane is a thin, flexible barrier made from silicone polymers, used in biology to separate materials while permitting controlled movement of selected gases, molecules, or fluids. Its performance depends on polymer structure, membrane thickness, pore characteristics when present, and the diffusion and solubility of substances within the silicone; unlike porous filters, many silicone membranes transport gases through the polymer itself. In biological research, these membranes support cell culture systems, organ-on-chip devices, biosensors, and controlled gas exchange, helping researchers model tissue environments, deliver compounds, or isolate experimental compartments.

Silicone Membrane - Related Videos

Research

JoVE Journal - Engineering

Fabrication and Characterization of High-Q Silicon Nitride Membrane Resonators

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Cited by 1 •

2025

This article traces the life cycle of a silicon nitride membrane resonator, from design through fabrication to characterization.

Research

JoVE Journal - Bioengineering
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Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

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2026

A novel sealing protocol to produce water-tight silicone-based seals for membranes of Polydimethylsiloxane (PDMS) chip devices. Intended for labs setting-up chip models and small-scale chip platform development. We demonstrate the protocol using plastic and native tissue membranes. This procedure only requires PDMS, toluene, mold, membrane, and a vacuum chamber.

Research

JoVE Journal - Engineering
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Fabrication Process of Silicone-based Dielectric Elastomer Actuators

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Cited by 102 •

2016

This manuscript shows the fabrication process for the manufacture of dielectric elastomer soft actuators based on silicone membranes. The three key stages of production are presented in detail: blade casting of thin silicone membranes; pad printing of compliant electrodes; and the assembly of all the components.

Research

JoVE Journal - Biochemistry
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Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis

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Cited by 16 •

2019

Presented here is a protocol for cell culture on silicon nitride membranes and plunge-freezing prior to X-ray fluorescence imaging with a synchrotron cryogenic X-ray nanoprobe. When only room temperature nano-analysis is provided, the frozen samples can be further freeze-dried. These are critical steps to obtain information on the intracellular elemental composition.

Fabrication and Optimization of Type II Silicon Clathrate Films

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2025

The two-thermal annealing method enables the fabrication of thin films of type II semiconductor silicon clathrate. Post-synthesis treatments, including thermal pressing and reactive ion etching, were performed to improve the material properties. This approach provides an accessible pathway for fabricating tunable clathrate films suitable for next-generation electronic and photonic devices.

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