Spinal Stenosis

Spinal stenosis is the narrowing of the spinal canal or nerve-root openings, a condition that can restrict space for the spinal cord and spinal nerves. It commonly develops when age-related changes, such as disc bulging, enlargement of facet joints, or thickening of spinal ligaments, reduce available space and compress neural tissues, sometimes causing pain, numbness, weakness, or difficulty walking. In biology and clinical research, spinal stenosis provides a model for studying how skeletal, connective, and nervous tissues interact during degeneration. Understanding these mechanisms supports diagnosis, symptom management, and the development of treatments that preserve neural function and mobility.

Spinal Stenosis - Related Videos

Research

JoVE Journal - Medicine

Surgical Management of Meatal Stenosis with Meatoplasty

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Cited by 13 •

2010

Meatoplasty, surgical management of meatal stenosis.

Percutaneous Endoscopic Unilateral-Approach Bilateral Decompression for Lumbar Spinal Stenosis

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Cited by 4 •

2024

The present protocol describes the steps and key points of lumbar endoscopic unilateral laminotomy for bilateral decompression for the treatment of degenerative lumbar spinal stenosis.

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

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Cited by 1 •

2023

Technical advances and increased experience in full-endoscopic spinal surgeries enable these procedures to be performed with minimal incision, muscle retraction, and bone removal.

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

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2025

Pulmonary vein stenosis (PVS) is a life-threatening complication of fibrosing mediastinitis (FM), with a poor prognosis if not properly treated. Currently, catheter-based endovascular angioplasty is a promising therapeutic strategy for FM-associated PVS. This protocol primarily outlines a stepwise approach to the transcatheter procedure for FM-associated PVS.

Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats

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Cited by 55 •

2012

We describe two tactile sensory testing methods for acute or chronic periods of spinal cord injury in rats. These validated procedures can detect the development and maintenance of allodynia-like sensations.

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