Tissue Slicer

A tissue slicer is a laboratory instrument used to cut biological tissues into thin, uniform sections for microscopic examination and experimental analysis. It works by guiding a sharp blade through a tissue sample under controlled movement and cutting conditions, producing slices that preserve cellular organization and tissue architecture. In biology, tissue slicers support histology, anatomy, neuroscience, and developmental research by preparing specimens for staining, imaging, and molecular assays. Consistent section thickness improves the quality and comparability of observations, helping researchers examine cell distribution, structural changes, and disease-related alterations across tissues.

Tissue Slicer - Related Videos

Research

JoVE Journal - Medicine

Working with Human Tissues for Translational Cancer Research

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Cited by 4 •

2015

Translational cancer research is dependent on extraction of human tissues. Much work has gone into optimizing extraction methods for ex vivo analysis. Here, we describe tissue processing methods allowing for maximal data output from limited samples.

Research

JoVE Journal - Bioengineering
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Tissue Engineering of a Human 3D in vitro Tumor Test System

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Cited by 34 •

2013

Methods to create human 3D tumor tissues as test systems are described. These technologies are based on a decellularized Biological Vascularized Scaffold (BioVaSc), primary human cells and a tumor cell line, which can be cultured under static as well as under dynamic conditions in a flow bioreactor.

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues

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Cited by 47 •

2016

This protocol describes the isolation of pig adipose-derived stem cells (pADSC) from subcutaneous adipose tissues with examination of multipotency. The multipotent pADSC are used to delineate processes of adipocyte differentiation and study transdifferentiation into multiple cell lineages of mesodermal mesenchyme or further lineages of ectoderm and endoderm for regenerative studies.

Research

JoVE Journal - Medicine
Free Sample

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation

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2025

This protocol offers a guide to implement infrared marker tracking for free-moving phantoms (e.g., organs) and holographic visualization using Augmented Reality. Additionally, it outlines a setup for preclinical validation of holographic navigation systems using electromagnetic tracking on free-moving phantoms.

Y-27632 Enriches the Yield of Human Melanocytes from Adult Skin Tissues

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Cited by 3 •

2020

This paper reports that the addition of Y-27632 to TIVA medium can significantly increase the yield of melanocytes from adult skin tissues.

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