4 Ms Framework

The 4 Ms Framework is an evidence-based approach to age-friendly clinical care that organizes assessment around four priorities: What Matters, Medication, Mentation, and Mobility. Clinicians identify each patient’s goals and preferences, review medications for safety and alignment with those goals, assess cognition and emotional well-being, and support movement and functional ability. By integrating these domains into routine care, the framework helps teams detect risks such as medication-related harm, delirium, dementia, depression, and functional decline while coordinating individualized interventions. Its use can improve communication, preserve independence, and promote care outcomes that reflect what matters most to older adults.

4 Ms Framework - Related Videos

Education

JoVE Science Education - Clinical Skills

The 4 M’s Framework: Case History and Physical Examination of Older Adults

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2023

Source: Jennifer A. Ouellet and Jaideep Talwalkar; Yale School of Medicine To meet the needs of older adults, all health professionals should be well acquainted with the history and physical examination considerations unique to this population. Physical examination plays an important role in the older patient to detect physiologic changes of aging, risk factors, and signs of pathology. While most of the general principles of the standard examination for adults apply to older patients, there are...

Research

JoVE Journal - Environment

Watershed Planning within a Quantitative Scenario Analysis Framework

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Cited by 1 •

2016

There is a critical need for tools and methodologies capable of managing aquatic systems in the face of uncertain future conditions. We provide methods for conducting a targeted watershed assessment that enables resource managers to produce landscape-based cumulative effects models for use within a scenario analysis management framework.

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 4. Medical Imaging Procedures

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Cited by 8 •

2016

Here, we present an overview of the preparation and animal handling procedures required to safely perform medical imaging in an animal biosafety level 4 laboratory. Computed tomography of a mock-infected guinea pig illustrates these procedures that may be used to evaluate the disease caused by a high consequence pathogen.

A Gaze-Contingent Display Framework for Perceptual Learning Research with Simulated Central Vision Loss

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Cited by 1 •

2025

We present development of a gaze-contingent display framework designed for perceptual and oculomotor research simulating central vision loss. This framework is particularly adaptable for studying compensatory behavioral and oculomotor strategies in individuals experiencing both simulated and pathological central vision loss.

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions

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2020

New routes for the synthesis of nitrogen-containing heterocycles utilizing cercosporin as a metal-free photocatalyst were developed.

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