Central Line Associated Blood Infection

Central line-associated bloodstream infection (CLABSI) is a serious healthcare-associated infection in which microorganisms enter the bloodstream while a central venous catheter is in place, causing preventable illness and added clinical risk. Microbes can reach the catheter through the insertion site, contaminated hands or equipment, or the catheter hub, then adhere to its surface and form biofilms that resist host defenses and antimicrobial treatment. In clinical practice, CLABSI definitions support infection surveillance and quality improvement, while sterile insertion, hand hygiene, skin antisepsis, hub disinfection, and prompt line removal when no longer needed reduce risk. Studying CLABSI strengthens catheter safety and patient outcomes.

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