Ileal Pouch-anal Anastomosis

Ileal pouch-anal anastomosis (IPAA) is a restorative surgical procedure that removes the colon and rectum and creates a new fecal reservoir from the terminal ileum, allowing stool to pass through the anus. During the operation, surgeons fold and staple a segment of ileum into a pouch, then connect it to the anal canal so intestinal contents can be stored and evacuated without a permanent ileostomy. IPAA is used mainly for medically refractory ulcerative colitis and selected patients with familial adenomatous polyposis. Its outcomes depend on pouch function, healing, continence, and complications such as pouchitis, making it important in colorectal surgery and postoperative care.

Ileal Pouch-anal Anastomosis - Related Videos

Research

JoVE Journal - Medicine

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

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2024

This protocol describes the method for establishing a rat model of pouchitis. The ileal pouch model was created by performing ileal pouch-anal anastomosis (IPAA) surgery using microsurgical techniques. After the surgery, the rat was treated with 4% dextran sulfate sodium (DSS) for 4 days.

Microsurgical Venous Pouch Arterial-Bifurcation Aneurysms in the Rabbit Model: Technical Aspects

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Cited by 11 •

2011

An optimized technique for the microsurgical creation of arterial bifurcation aneurysms mimicking bifurcation human cerebral aneurysms is described. A venous pouch is sutured into an artificially created true bifurcation of both common carotid arteries. Facilitated microsurgical techniques and aggressive postoperative anticoagulation and analgesia lead to minimized morbidity rates and high aneurysm patency rates.

Research

JoVE Journal - Medicine
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The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage

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Cited by 8 •

2010

The C-seal is a biofragmentable drain protecting the stapled colorectal anastomosis. In this video, details of the manufacturing, deployment and use are shown.

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice

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Cited by 1 •

2023

Single-anastomosis duodeno-ileal bypass (SADI-S) is an emerging bariatric procedure with important metabolic effects. In this article, we present a reliable and reproducible model of SADI-S in mice.

Murine Ileal Resection Model: Studying Ileectomy-Induced Bile Metabolism in Murine Model

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2023

This video describes the detailed protocol for intestinal resection in a murine model. This technique provides insights into ileectomy-induced bile malabsorption, overaccumulation, and toxicity in the mouse intestine.

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