Intra-arterial Catheter

An intra-arterial catheter is a thin, flexible tube placed within an artery to provide direct vascular access for continuous monitoring and selected clinical procedures. Once positioned, blood pressure pulses travel through the fluid-filled catheter to a pressure transducer, which converts them into a real-time arterial waveform and numerical pressure readings; the catheter may also permit repeated arterial blood sampling. In clinical care, this method supports close hemodynamic assessment in critically ill patients, during anesthesia, and in settings requiring frequent blood-gas analysis. Accurate placement, secure fixation, sterile technique, and ongoing assessment help reduce complications and maintain reliable measurements.

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In this video, we demonstrate intra-renal drug administration in rats via the renal artery. This method is beneficial in improving drug targeting, drug potency, and minimizing systemic toxicity.

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In this video, we have demonstrated a step-by-step procedure of pulmonary artery catheterization by inserting an intravascular catheter through jugular vein and reach the pulmonary artery to measure the cardiac chamber pressure in porcine model.

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis

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Cited by 43 •

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This manuscript provides the detailed procedure of intra-iliac artery (IIA) injection, a technique to deliver cancer cells specifically to hind limb tissues including bones to establish experimental bone metastases. Although initially established with breast tumor models, this protocol can be easily extended to other cancer types.

Research

JoVE Journal - Medicine
Free Sample

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Cited by 29 •

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Hypoxic pulmonary vasoconstriction (HPV) is an important physiological phenomenon by which at alveolar hypoxia lung perfusion is matched to ventilation. The major vascular segment contributing to HPV is the intra-acinar artery. Here, we describe our protocol for the analysis of HPV of murine pulmonary vessels with diameters of 20-100 μm.

Education

JoVE Science Education - Clinical Skills

Arterial Line Placement

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2023

Source: Sharon Bord, MD, Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA When monitoring patients, it is important to obtain values that are accurate and reliable. Blood pressure monitoring is one of the essential vital signs, and for a majority of patients, measuring it utilizing non-invasive techniques provides accurate values. However, there are situations in which the blood pressure requires more exact, specific, and reliable measurements.

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