Intra-cardiac Pressure Measurement
Intra-cardiac Pressure Measurement - Related Videos
07:38
Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect
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Cited by 10 •
2015
This article describes the measurement of murine left ventricular function via pressure/volume analysis at different heart rates.
08:15
Cardiac Pressure-Volume Loop Analysis Using Conductance Catheters in Mice
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Cited by 33 •
2015
Cardiac pressure-volume loop analysis is the most comprehensive way to measure cardiac function in the intact heart. We describe a technique to perform and analyze cardiac pressure volume loops, using conductance catheters.
09:15
Measuring Pressure Volume Loops in the Mouse
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Cited by 16 •
2016
This manuscript describes a detailed protocol for the collection of pressure-volume data from the mouse.
09:31
Noninvasive Blood Pressure Measurement Techniques
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2023
Source: Hamna J. Qureshi and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana Here we will highlight the key similarities and differences of noninvasive blood pressure measurement techniques between humans and rodents and examine the engineering principles that govern blood pressure. The principles that govern current cuff technology to acquire systolic and diastolic pressures will also be discussed. Commercially available cuffs that connect...
03:34
Spatial Measurement of Tumor Interstitial Fluid Pressure: A Method to Measure the Interstitial Fluid Pressure
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2023
This video describes a technique of measuring the interstitial fluid pressure within a tumor by perfusion imaging using an image-guided robotic system. Measurements are compared to the intra-tumoral accumulation of liposomes, within a solid tumor.
FAQs
The catheter’s pressure sensor responds to changes at the selected location, while the transducer converts those changes into electrical signals. The resulting waveform can be recorded and analyzed rather than relying on a single pressure value. This preserves information about the pressure pattern within each chamber or great vessel and supports hemodynamic interpretation.
Comparing pressures across cardiac chambers and great vessels allows clinicians to evaluate differences, or gradients, between locations. An abnormal gradient can point toward outflow obstruction, while unusual relationships between chambers may support assessment of shunt-related abnormalities. These comparisons add anatomical and functional context that an isolated pressure reading cannot provide.
Each chamber or great vessel represents a different part of cardiac and vascular hemodynamics. Recording from selected locations permits assessment of filling, outflow, and ventricular performance in relation to one another. This site-specific approach helps distinguish whether an abnormal finding is associated with filling, obstruction, shunting, or impaired ventricular function.
During a catheterization procedure, the catheter is advanced through the vascular system into the cardiac chamber or great vessel being evaluated. At each selected location, the pressure signal can be captured for waveform recording and analysis. The workflow links catheter position with a specific hemodynamic measurement, allowing findings from different sites to be compared.
It is useful when clinicians need hemodynamic information in conditions such as valvular heart disease, congenital heart disease, pulmonary hypertension, or advanced heart failure. The measurements can clarify how disease affects pressures and pressure relationships within the heart and great vessels, supporting diagnostic evaluation and helping clinicians plan appropriate treatment or procedures.
Pressure findings can help connect a suspected disorder with its functional consequence. Evidence of abnormal filling, an outflow gradient, a shunt-related pressure relationship, or impaired ventricular performance may refine the clinical assessment. In this way, the study contributes not only to diagnosis, but also to treatment planning and decisions about cardiac procedures.