Lymphoid Hyperplasia
Lymphoid Hyperplasia - Related Videos
08:34
Inducing Myointimal Hyperplasia Versus Atherosclerosis in Mice: An Introduction of Two Valid Models
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Cited by 8 •
2014
This video shows two models of intimal plaque development in murine arteries and emphasizes the differences in myointimal hyperplasia and atherosclerosis.
04:33
Carotid Artery and Jugular Vein Interposition: A Technique to Induce Venous Intimal Hyperplasia in Rabbit Model
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2025
This video demonstrates the interposition of the rabbit carotid artery with the jugular vein to induce venous intimal hyperplasia by subjecting the veins to arterial pressure. This model will help investigate molecular and genetic interventions to attenuate the progression of intimal hyperplasia after revascularization surgeries.
04:39
In Vitro Generation of Plasmacytoid Dendritic Cells from Common Lymphoid Progenitors
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2025
This video demonstrates an in vitro assay to generate plasmacytoid dendritic cells (pDCs) from common lymphoid progenitor cells (CLPs). Upon co-culturing purified CLPs with γ-irradiated feeder cells in the presence of Fms-like tyrosine kinase-3 ligand (FL), the CLPs differentiate into non-adherent pDCs, the presence of which is confirmed using flow cytometry.
01:18
Lymphoid Cells and Tissues
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2024
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes. Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
01:15
Secondary Lymphoid Organs
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2024
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection. The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
FAQs
Antigenic stimulation, infection, and inflammation can drive lymphocyte proliferation within existing lymphoid structures. The resulting response may be confined to one site or involve several regions, depending on the distribution of the underlying stimulus. This mechanism explains why enlargement can appear in lymph nodes, tonsils, the spleen, or mucosa-associated lymphoid tissue.
Pattern is clinically informative because enlargement may be localized or generalized. A localized finding directs attention to the affected lymphoid region, whereas generalized involvement indicates that more than one area is enlarged. Considering the involved structure, such as a node, tonsil, spleen, or mucosal site, helps organize interpretation of the clinical presentation.
Cellular features help determine whether an enlarged mass reflects a reactive immune response or a process such as lymphoma or another malignancy. Their interpretation can also provide clues about the underlying infectious or inflammatory condition. Thus, cellular assessment supports classification of the enlargement and selection of appropriate further evaluation.
When Lymphoid Hyperplasia is suspected, evaluation can begin with the clinical history and may incorporate imaging, laboratory testing, or biopsy. These approaches are complementary: history supplies clinical context, imaging characterizes the finding, laboratory studies support assessment of associated conditions, and biopsy permits examination of tissue and cellular features.
Biopsy is useful when tissue and cellular features must be assessed to distinguish reactive enlargement from lymphoma or another malignancy. It can also help relate the observed pattern to an underlying immune or infectious condition. In clinical practice, tissue examination can therefore help resolve uncertainty after history, imaging, or laboratory assessment.
The distribution and cellular features of lymphoid enlargement can provide insight into an underlying immune, infectious, or inflammatory condition. Localized or generalized patterns may help frame the clinical question, while tissue findings can support interpretation of the response. These observations guide decisions about whether additional history, imaging, laboratory testing, or biopsy is needed.