Pain Management

Pain management is the clinical assessment and treatment of acute or chronic pain to reduce suffering, restore function, and improve quality of life. It begins with identifying pain’s intensity, duration, source, and effects, then uses targeted interventions such as analgesic medications that modify nociceptive signaling alongside physical, psychological, or interventional therapies. Multimodal care can address inflammatory, neuropathic, and musculoskeletal pain while limiting treatment-related risks, including medication adverse effects. In clinical practice, individualized pain management supports recovery after injury or surgery and helps patients manage persistent conditions through ongoing evaluation and adjustment.

Pain Management - Related Videos

Education

JoVE Science Education - Basic Biology

Early Intervention and Pain Management

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2026

All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Monitoring Animals for Signs of Pain and Distress Recognizing early signs of pain is essential for ethical animal research. Animals are routinely monitored using behavioral, physical, and physiological parameters that reflect...

Research

JoVE Journal - Medicine
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Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity

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Cited by 9 •

2013

The purpose is to present a new method, breathing-control electrical stimulation (BreEStim) for management of neuropathic pain and spasticity.

Analgesia and Pain Management

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2024

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

Research

JoVE Journal - Neuroscience
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Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

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Cited by 4 •

2023

Current pain scales used to quantify pain severity, such as visual analog scales, fail to capture the complexity of subjective pain experiences. Pain body diagrams are qualitative but may be more informative. The goal of this method is to extract quantitative metrics from pain body diagrams using novel pressure-hue transformation.

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management

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Cited by 1 •

2025

Recent developments in pain research highlight the potential of photoneuromodulation using green light-emitting diodes (GLED) as a non-pharmacological treatment. GLED modulates pain pathways, offering effective pain relief. This article aims to standardize and refine GLED exposure protocols, improving consistency across studies and advancing the clinical application of this therapy.

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