Multi-compartment Phantom

A multi-compartment phantom is a physical model containing two or more distinct, often interconnected compartments that reproduce selected structural or material features of a real system for controlled engineering studies. By separating compartments with defined boundaries, interfaces, or flow pathways, researchers can independently adjust conditions and measure how signals, substances, or mechanical effects move between regions. These phantoms support calibration, validation, and performance testing of imaging systems, sensors, and experimental methods while reducing dependence on complex biological or industrial samples. Their controlled geometry and repeatable properties also help isolate variables, compare designs, and improve the reliability of engineering measurements.

Multi-compartment Phantom - Related Videos

Research

JoVE Journal - Engineering

Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents

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Cited by 5 •

2016

A multi-compartment dynamic phantom is used to simulate some biology of interest for metabolic studies using hyperpolarized magnet resonance agents.

A Multi-compartment CNS Neuron-glia Co-culture Microfluidic Platform

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Cited by 18 •

2009

We developed a novel multi-compartment neuron co-culture microsystem platform for in vitro CNS axon-glia interaction research. The platform is capable of conducting up to six independent experiments in parallel and was fabricated using a newly developed macro/micro hybrid fabrication method.

Research

JoVE Journal - Biology
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Preparation and Using Phantom Lesions to Practice Fine Needle Aspiration Biopsies

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Cited by 6 •

2009

Practicing of fine needle aspiration biopsies (FNAB) by trainees is relatively challenging, due to the lack of an easily available, appropriate lesion. Preparation of an AV phantom lesion for practicing the FNAB procedure and mastering proficiency is relatively easy.

Education

JoVE Core - Pharmacology

Compartment Models: Two-Compartment Model

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2025

The two-compartment model divides the body into central and peripheral compartments to account for varying blood perfusion rates among organs and tissues, affecting drug distribution. The central compartment includes blood and highly perfused tissues with rapid drug distribution, while the peripheral compartment contains tissues with slower drug distribution. After a single IV bolus dose, the drug concentration is high in plasma and low in tissues. The drug distribution between compartments...

Anisotropic Polyvinyl Alcohol Phantom Fabrication for Ultrasound Elastography: Procedure and Quality Controls

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2026

This protocol describes a robust, reproducible method for fabricating anisotropic polyvinyl alcohol (PVA) phantoms—essential tools for validating ultrasound elastography techniques targeting mechanically anisotropic soft tissues (e.g., skeletal muscle).

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