Process Parameter Optimization

Process parameter optimization is the systematic adjustment of operating conditions to improve the performance, quality, efficiency, or consistency of an engineering process. It works by identifying influential variables, such as temperature, pressure, flow rate, feed rate, or processing time, then evaluating how their individual and combined effects influence defined performance objectives. Engineers use experiments, process models, statistical analysis, and iterative testing to establish suitable parameter settings while considering constraints and trade-offs. This approach supports reliable manufacturing, energy reduction, waste minimization, product quality control, and scalable process design across chemical, mechanical, materials, and industrial engineering applications.

Process Parameter Optimization - Related Videos

Research

JoVE Journal - Bioengineering
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Electrospinning Fundamentals: Optimizing Solution and Apparatus Parameters

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Cited by 93 •

2011

Electrospinning techniques can create a variety of nanofibrous scaffolds for tissue engineering or other applications. We describe here a procedure to optimize the parameters of the electrospinning solution and apparatus to obtain fibers with the desired morphology and alignment. Common problems and troubleshooting techniques are also presented.

Research

JoVE Journal - Cancer Research

Optimization of Performance Parameters of the TAGGG Telomere Length Assay

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Cited by 3 •

2023

Here, we describe in detail the protocol for quantifying telomere length using non-radioactive chemiluminescent detection, with a focus on the optimization of various performance parameters of the TAGGG telomere length assay kit, such as buffer quantities and probe concentrations.

Wicking Tests for Unidirectional Fabrics: Measurements of Capillary Parameters to Evaluate Capillary Pressure in Liquid Composite Molding Processes

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Cited by 3 •

2017

An experimental method to measure geometrical parameters and the apparent advancing contact angles describing capillary wicking in unidirectional synthetic and natural fabrics is proposed. These parameters are mandatory for the determination of the capillary pressures that must be taken into account for liquid composite molding (LCM) applications.

Research

JoVE Journal - Chemistry
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Spin Saturation Transfer Difference NMR (SSTD NMR): A New Tool to Obtain Kinetic Parameters of Chemical Exchange Processes

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Cited by 4 •

2016

A detailed protocol describing the SSTD NMR method is presented here to help new users apply this new method to obtain the kinetic parameters of their own systems undergoing chemical exchange.

Optimization of Flow Cytometric Sorting Parameters for High-Throughput Isolation and Purification of Small Extracellular Vesicles

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Cited by 2 •

2023

This protocol provides a rapid and size-specific isolation method for small extracellular vesicles by optimizing the size of the air spray nozzle, sheath fluid pressure, sample flow pressure, voltage, gain, and triggering threshold parameters.

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