Silica Microsphere
Silica Microsphere - Related Videos
07:51
Fabrication of Silica Ultra High Quality Factor Microresonators
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Cited by 22 •
2012
We describe the use of a carbon dioxide laser reflow technique to fabricate silica resonant cavities, including free-standing microspheres and on-chip microtoroids. The reflow method removes surface imperfections, allowing long photon lifetimes within both devices. The resulting devices have ultra high quality factors, enabling applications ranging from telecommunications to biodetection.
09:35
Attaching Biological Probes to Silica Optical Biosensors Using Silane Coupling Agents
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Cited by 13 •
2012
Biosensors interface with complex, biological environments and perform targeted detection by combining highly sensitive sensors with highly specific probes attached to the sensor via surface modification. Here, we demonstrate the surface functionalization of silica optical sensors with biotin using silane coupling agents to bridge the sensor and the biological environment.
04:02
Spherical Supported Lipid Bilayer Assay: A Technique to Observe the Septin Assembly on Microspheres
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2025
This video describes the technique of studying the septin protein assembly on microspheres coated with lipid bilayers. This technique helps in understanding the curvature-dependent assemblies of protein on curved surfaces.
12:21
Stimulated Stokes and Antistokes Raman Scattering in Microspherical Whispering Gallery Mode Resonators
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Cited by 1 •
2016
Efficient generation of nonlinear phenomena related to third order optical non-linear susceptibility Χ(3) interactions in triply resonant silica microspheres is presented in this paper. The interactions here reported are: Stimulated Raman Scattering (SRS), and four wave mixing processes comprising Stimulated Anti-stokes Raman Scattering (SARS).
08:06
Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications
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Cited by 3 •
2017
Protocols for the synthesis of microspheres from polymers, the manipulation of microspheres, and micro-photoluminescence measurements are presented.
FAQs
During sol-gel synthesis, silica precursors first undergo hydrolysis and then condensation, creating the particle’s inorganic network. Adjusting reaction conditions and adding selected additives changes how quickly these reactions proceed and how the structure develops. Engineers therefore use synthesis control to tune microsphere size, porosity, and surface chemistry for targeted transport or binding behavior.
Porosity determines how readily molecules or fluids can access internal regions, while particle size influences the scale of interfaces and transport pathways. Surface chemistry governs interactions at those interfaces, including binding behavior. Controlling these features together allows a silica microsphere system to be adapted for separation, catalysis, delivery, or sensing rather than treated as a one-property material.
A high surface area provides more accessible interface for interactions with surrounding species. Combined with chemical stability and modifiable surfaces, this characteristic supports binding and helps maintain performance under the intended use. The same interfacial advantages explain their selection as catalyst supports, chromatography stationary phases, and carriers in controlled drug-delivery designs.
The central workflow uses silica precursors that undergo hydrolysis and condensation, while reaction conditions and additives are varied to control the resulting structure. These adjustments can influence particle size, porosity, and surface chemistry. In practice, the desired combination depends on whether the microspheres must promote transport, provide binding behavior, or present a stable engineered interface.
In catalyst supports, the particles provide a structured material for hosting catalytic components; in chromatography, they function as stationary phases for separation; and in controlled drug delivery, they act as carriers. Their tunable porosity and surface chemistry help regulate interactions and transport, while chemical stability supports use across these different engineering systems.
Their role comes from combining controllable particle structure with modifiable surface chemistry and stable silica composition. Those features let engineers tailor interfacial behavior and transport for a device or coating, while supporting functional material design in photonic systems. Consequently, the microspheres serve as engineered functional materials rather than merely passive fillers, with performance linked to their structure.