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Bioengineering

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Attaching Biological Probes to Silica Optical Biosensors Using Silane Coupling Agents

Article DOI: 10.3791/3866
May 1st, 2012 •
1, 1
1Department of Biological Engineering, University of Missouri

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May 1st, 2012

Biosensors interface with complex, biological environments and perform targeted detection by combining highly sensitive sensors with highly specific probes attached to the sensor via surface modification. Here, we demonstrate the surface functionalization of silica optical sensors with biotin using silane coupling agents to bridge the sensor and the biological environment.

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