High Throughput Processing

High-throughput processing is an approach for rapidly handling and analyzing large numbers of samples, measurements, or experimental conditions, making it valuable when environmental studies must characterize complex systems at scale. It increases capacity by combining standardized sample preparation, parallel or automated workflows, miniaturized reactions, and data-management systems that reduce manual handling while maintaining consistent conditions. In environmental research, these methods support broad screening of water, soil, sediment, and biological samples for pollutants, nutrients, or biological responses, helping researchers compare sites, identify trends, and prioritize detailed analyses. Reliable quality controls remain essential because processing speed must be balanced with measurement accuracy and reproducibility.

High Throughput Processing - Related Videos

Research

JoVE Journal - Biology

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes

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2015

Here we describe a cell-based reporter gene assay as a valuable tool to screen chemical libraries for compounds modulating post-transcriptional control mechanisms exerted through 3’ UTR.

Research

JoVE Journal - Biochemistry
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High-Throughput Screening to Obtain Crystal Hits for Protein Crystallography

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Cited by 16 •

2023

This protocol details high-throughput crystallization screening, ranging from the 1,536 microassay plate preparation to the end of a 6 week experimental time window. Details are included about the sample setup, the imaging obtained, and how users can perform analyses using an artificial intelligence-enabled graphical user interface to quickly and efficiently identify macromolecular crystallization conditions.

Research

JoVE Journal - Environment
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High-throughput, Microscale Protocol for the Analysis of Processing Parameters and Nutritional Qualities in Maize (Zea mays L.)

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Cited by 2 •

2018

Here, we present a microscale protocol for processing grain samples and for incorporating this microscale approach into a high-throughput analytical pipeline. This is a higher throughput adaptation of currently available protocols.

Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation

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Cited by 1 •

2020

Here, we present a detailed procedure to run a Design of Experiment in an automated micro-bioreactor followed by cell harvest and protein quantification using a Protein A column.

High-Throughput, Multi-Image Cryohistology of Mineralized Tissues

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Cited by 117 •

2016

In this manuscript, we present a high-throughput, semi-automated cryohistology platform to produce aligned composite images of multiple response measures from several rounds of fluorescent imaging on frozen sections of mineralized tissues.

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