Clinical Assessment Methodology

Clinical assessment methodology is a structured approach to collecting and interpreting patient information to identify health problems, guide diagnosis, and support safe clinical decisions. It combines the medical history, physical examination, vital signs, and appropriate diagnostic tests, using clinical reasoning to organize findings, estimate disease likelihood, and develop a differential diagnosis. In medicine, clinicians apply this process to recognize urgent conditions, select targeted investigations, establish management plans, and monitor responses over time. Consistent assessment methods improve communication, reduce diagnostic error, and provide a foundation for evidence-based, patient-centered care across clinical settings.

Clinical Assessment Methodology - Related Videos

Research

JoVE Journal - Medicine

A Methodological Protocol and Considerations for Transcranial Ultrasonic Stimulation in Exploratory Clinical Human Studies

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2025

Transcranial ultrasonic stimulation (TUS) is a promising non-invasive technique capable of stimulating the human brain at any depth, offering new therapeutic possibilities to treat various neurological conditions. This protocol provides a standardized yet adaptable empirical framework for applying TUS in neurotypical adults and patients with neurological diseases such as stroke.

Research

JoVE Journal - Behavior
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Practical Methodology of Cognitive Tasks Within a Navigational Assessment

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Cited by 1 •

2015

Children who have complex communication needs can benefit from the use of a speech-generating device (SGD). Cognitive skills were identified as having an impact on the ability to navigate between levels of SGDs. This protocol describes the steps needed for Speech-language Pathologists to assess cognitive skills and navigational abilities.

Research

JoVE Journal - Medicine
Free Sample

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology

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Cited by 16 •

2015

The present article describes the methodological considerations for several non-invasive assessments of vascular function and morphology that are commonly used in medical research to assess different stages of atherosclerosis.

Education

JoVE Science Education - Basic Biology

Introduction to New Approach Methodologies (NAMs)

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2026

All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. New approach methodologies (NAMs) are innovative scientific approaches that generate biological data while reducing reliance on traditional vertebrate animal models. As part of the broader effort to implement the principles of...

Human Egg Maturity Assessment and Its Clinical Application

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Cited by 14 •

2019

We provide an outline of the clinical protocol for non-invasive assessment of human egg maturity using polarized light microscopy.

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