Function-preserving Surgery

Function-preserving surgery is an operative approach that removes or repairs diseased tissue while maintaining as much normal anatomy and physiological function as possible. Surgeons achieve this balance through precise preoperative planning, tissue-sparing dissection, reconstruction, and, when appropriate, intraoperative imaging or monitoring to identify critical nerves, vessels, and functional structures. In medicine, this approach can reduce treatment-related disability, support recovery, and improve quality of life, particularly when surgery involves regions responsible for movement, sensation, speech, swallowing, or hormonal activity. It also drives advances in minimally invasive techniques and personalized surgical decision-making.

Function-preserving Surgery - Related Videos

Research

JoVE Journal - Medicine
Free Sample

Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion

0 Views •

Cited by 29 •

2015

We describe a method of ex vivo machine perfusion of human liver grafts at subnormothermic temperature (21 °C).

Research

JoVE Journal - Immunology and Infection

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

0 Views •

Cited by 17 •

2014

One key to successful investigation of microglial biology is the preservation of microglial immunofunction ex vivo during isolation from CNS tissue. Isolating microglia via rotary shaking results in highly pure and immunofunctional cell cultures as assessed by fluorescent imaging, immunocytochemistry, and ELISA following microglia activation with the proinflammatory stimuli lipopolysaccharide (LPS) and Pam3CSK4 (Pam).

Innovative Strategies for Organ Preservation in Heart Transplantation: Uniform Cooling Preservation and Ex-situ Normothermic Perfusion

0 Views •

2025

Donor heart preservation is a major determinant of success in heart transplantation. Technological advances have led to optimizing the conditions of preservation, along with a more accurate assessment of the donor heart before transplantation. We herein describe two innovative technologies currently applied for cardiac preservation: uniform cooling preservation and normothermic ex-situ heart perfusion.

Ex Situ Heart Perfusion: A Technique to Preserve Isolated Porcine Heart Function

0 Views •

2025

This video describes an ex situ technique for preserving an isolated porcine heart by perfusing it with an oxygenated nutrient-rich perfusate solution. The technique allows the comprehensive evaluation of cardiac performance under physiological conditions.

Education

JoVE Science Education - Basic Biology

Considerations for Rodent Surgery

0 Views •

2016

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN The Guide for the Care and Use of Laboratory Animals1 dictates that rodent survival surgery be performed aseptically. Aseptic technique utilizes specific practices that minimize the contamination of the surgical site, including patient preparation, surgeon preparation, sterilization of instruments and other supplies, and the use of a clean and controlled environment. Presurgical planning,...

View All Results

FAQs

Related Topics