Lidocaine Topical Anesthesia

Lidocaine topical anesthesia is a method of producing temporary loss of sensation in a localized area by applying lidocaine to the skin or mucous membranes, reducing pain during minor medical procedures. Lidocaine diffuses into nearby nerve endings and blocks voltage-gated sodium channels, preventing membrane depolarization and the transmission of pain signals along sensory nerves. It is available in formulations such as creams, gels, ointments, sprays, and patches, supporting applications in dermatology, dentistry, wound care, and diagnostic procedures. Its localized action can improve patient comfort while limiting the broader effects associated with systemic or general anesthesia.

Lidocaine Topical Anesthesia - Related Videos

Research

JoVE Journal - Medicine

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

0 Views •

Cited by 11 •

2017

The topical anesthetic lidocaine was atomized using a high oxygen flow through the working channel of a flexible intubating endoscope to achieve topical airway anesthesia for awake endotracheal intubation. We prefer this modified spray-as-you-go technique for endoscopic intubation to classical bolus application because of higher patient satisfaction and better compliance.

Education

JoVE Science Education - Basic Biology

Anesthesia Induction and Maintenance

0 Views •

2016

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN The Guide for the Care and Use of Laboratory Animals ("The Guide") states that pain assessment and alleviation are integral components of the veterinary care of laboratory animals. The definition of anesthesia is the loss of feeling or sensation. It is a dynamic event involving changes in anesthetic depth with respect to an animal's metabolism, surgical stimulation, or variations in the...

Topical Testing Assay: A Technique to Evaluate the Insecticidal Potential of Dopamine Receptor Antagonists on Adult Female Mosquitoes by Topical Application

0 Views •

2025

In this video, we demonstrate the topical testing assay to determine the toxicity of a potential insecticide on adult female mosquitoes. Using a dopamine receptor antagonist that causes lethal inhibition of neurotransmission in mosquitoes, this method describes a way to evaluate the toxic effects of insecticides upon topical application.

Research

JoVE Journal - Neuroscience
Free Sample

Generation of Topically Transgenic Rats by In utero Electroporation and In vivo Bioluminescence Screening

0 Views •

Cited by 7 •

2013

Genes can be manipulated during development of the cortex or the hippocampus of the rat via in utero electroporation (IUE) at E16, to enable fast and targeted modifications in neuronal connectivity for later studies of behavior or neuropathology in adult animals. Postnatal in vivo imaging for control of IUE success is performed by bioluminescence of activating co-transfected luciferase.

Anesthesia and Monitoring in a Rabbit Model

0 Views •

2026

All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Anesthesia is an essential component of rabbit surgical and experimental procedures because it prevents pain, reduces stress responses, and helps immobilize the animal during handling and manipulation when general anesthesia is...

View All Results

FAQs

Related Topics