Obese Patient Surgery

Obese patient surgery refers to the perioperative planning and surgical care of patients with obesity, whose altered anatomy and physiology can increase technical difficulty and the risk of complications. Excess adipose tissue can reduce functional residual capacity, impair airway management and ventilation, and change drug distribution, while increased mechanical load may complicate positioning, access, and postoperative mobility. Safe care therefore combines individualized risk assessment with appropriate operating-table and positioning strategies, airway and anesthetic planning, thromboprophylaxis, and enhanced respiratory monitoring. These principles support safer procedures across specialties and help teams reduce respiratory, cardiovascular, wound, and thromboembolic complications while improving recovery.

Obese Patient Surgery - Related Videos

Education

JoVE Core - Pharmacokinetics and Pharmacodynamics

Drug Dosing: Obese Patients

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2025

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

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2025

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

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2025

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...

Research

JoVE Journal - Medicine

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

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2024

Duodenal-jejunal bypass (DJB) surgery can improve glucose metabolism and reduce insulin resistance. Here, we present a protocol to establish a stable and reliable mouse model of DJB.

Obesity

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2024

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...

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