Ovaries Excision
Ovaries Excision - Related Videos
01:54
Base Excision Repair
0 Views •
2020
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template. The first step of...
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Obtaining Primary Ovarian Cancer Cells from Solid Specimens: A Method to Culture Epithelial Ovarian Cancer Cells from Ovarian Tumor Specimens
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In this video, we describe a method for isolating and characterizing primary ovarian cancer cells from solid ovarian tumor tissue specimens. The epithelial cancer cells obtained using this protocol are suitable for understanding the processes that may lead to ovarian cancer initiation and development.
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An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
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Cited by 18 •
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To study in vivo tumor growth and tumor microenvironment, we used a syngeneic and orthotopic mouse model of ovarian cancer in immunocompetent animals. We transduced a mouse tumor cell line (MOV1) with Katushka fluorescent protein (MOV1KAT) and here we show its orthotopic implantation in ovary and in vivo imaging.
09:25
Transplantation Into the Mouse Ovarian Fat Pad
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Cited by 7 •
2016
We describe an ovarian fad pad transplantation assay suitable for studies of normal and transformed epithelia of the female reproductive tract. The mouse fat pad allows transplantation of large tissue fragments, is easily accessible for surgery and imaging, and provides the most favorable native environment for tissues of Müllerian origin.
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Ovarian Fat Pad Transplantation Assay: An In Vivo Technique to Introduce Cells into Ovarian Fat Pad in Mouse Models
0 Views •
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In this video, we demonstrate an assay for transplantation of experimental cells and tissue fragments into the mouse ovarian fat pad. This method can be used to monitor cell regeneration and tumor transformation via non-invasive techniques.
FAQs
Removing one ovary does not necessarily eliminate ovarian hormone production, whereas removing both ends production from the ovaries and causes surgical menopause. This distinction affects clinical planning because bilateral surgery requires attention to menopausal symptoms, fertility implications, and longer-term health effects. The number of ovaries removed therefore influences counseling, risk assessment, and follow-up needs.
The ovary is connected to supporting tissues and a blood supply that must be separated during surgery. Careful control of these connections helps manage bleeding while allowing the surgical specimen to be removed. This anatomical step is central to safe operative technique and applies whether surgeons reach the pelvis through laparoscopic access or an open approach.
Ovaries excision can be performed through laparoscopic or open surgery, representing different ways to access the pelvis. The selected approach forms part of the operative plan and must accommodate the condition being treated, the intended specimen removal, and control of bleeding. The source material identifies both approaches but does not specify a universal choice for every patient.
Clinical indications include ovarian cancer, persistent cysts, endometriosis, and ovarian torsion. These conditions differ in their medical context, but each can prompt consideration of surgical removal when treatment requires addressing the affected ovary. Inherited susceptibility to cancer represents another context, where surgery may be considered primarily to reduce a specific future health risk.
The procedure begins with pelvic access, using either laparoscopic or open surgery. The surgeon then separates the ovary from its supporting tissues and blood supply, controls bleeding, and removes the surgical specimen. These steps describe the essential operative sequence without determining whether one or both ovaries are removed, since that decision depends on the clinical indication and plan.
Assessment before removal of both ovaries is important because bilateral surgery ends ovarian hormone production and causes surgical menopause. Planning should therefore address fertility as well as expected symptoms and longer-term health effects. These considerations help clinicians and patients weigh the intended treatment or risk reduction against consequences that follow from loss of ovarian function.
For people with an inherited susceptibility to cancer, removing the ovaries may lower a specific cancer risk rather than treat an already diagnosed tumor. This preventive context differs from surgery for ovarian cancer, persistent cysts, endometriosis, or torsion. The decision still requires clinical planning because bilateral removal ends ovarian hormone production and causes surgical menopause.