Pancreatic Head Tumor
Pancreatic Head Tumor - Related Videos
10:10
Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
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2026
This protocol presents robotic duodenum-preserving total pancreatic head resection (R-DPPHRt) for intraductal papillary mucinous neoplasms (IPMNs). A video demonstrates the technique in a patient with main duct-IPMN, highlighting its feasibility as a minimally invasive, organ-preserving alternative to pancreaticoduodenectomy.
05:11
Treatment of Middle-segment Pancreatic Benign Tumor Using Laparoscopic Central Pancreatectomy with End-to-end Pancreatic Duct Reconstruction
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2026
This article presents laparoscopic central pancreatectomy with pancreatic duct end-to-end anastomosis as an important surgical approach for middle-segment pancreatic benign and low-grade malignant tumors.
03:59
Orthotopic Homograft Tumor Transplantation: A Technique to Generate Pancreatic Tumor Mouse Models
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2023
The video explains a stepwise surgical method for orthotopic implantation of a tumor fragment from a cancerous donor to the pancreas of a non-cancerous recipient mice for development of pancreatic cancer. Orthotopically implanted PDAC could recapture the tissue microenvironment of human pancreatic cancers than conventional subcutaneous (SC) models more accurately.
03:50
Irreversible Electroporation: A Technique for Ablating Pancreatic Tumor in Mouse
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2023
This video describes the procedure for performing irreversible electroporation (IRE) for non-thermal ablation of pancreatic tumors in mice. Both subcutaneous (SQ) and orthotopic tumors can be successfully treated with IRE in a highly controlled setting, facilitating various studies post-procedure.
09:18
Multianimal Magnetic Resonance Imaging for Tumor Measurements in Pancreatic Cancer Mouse Models
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2026
This protocol uses a multichamber bed for parallel magnetic resonance imaging (MRI) of up to four animals to detect pancreatic adenocarcinoma tumors in genetically engineered mouse models. This multianimal MRI protocol is fast and cost-effective for detecting and measuring tumors, facilitating animal selection for preclinical studies and longitudinal monitoring of tumor growth.
FAQs
As a lesion enlarges, it can compress or invade the common bile duct and pancreatic duct. Narrowing these channels interferes with the movement of bile and digestive enzymes, linking the tumor’s local growth to impaired duct function. This anatomic effect is important because clinicians assess both the lesion itself and the nearby pathways it may obstruct.
Local invasion indicates that the growth may extend beyond its original site into adjacent tissues, including structures near the pancreatic head. Assessment also considers whether disease has reached distant organs. These findings help characterize the tumor’s extent and stage, which directly influences whether treatment can focus on surgical removal, systemic therapy, or palliation.
The pancreatic head lies close to the bile duct, duodenum, pancreatic duct, and major blood vessels. Consequently, evaluation must consider relationships with several critical structures rather than tumor size alone. These anatomic relationships help determine the lesion’s effects, its stage, and the feasibility or purpose of options such as pancreaticoduodenectomy or nonoperative treatment.
Clinical evaluation combines imaging, laboratory tests, and tissue sampling. Imaging helps characterize the lesion and its anatomic relationships, while laboratory testing contributes additional clinical information. Tissue sampling provides cellular evidence about the growth. Together, these approaches support characterization and staging rather than relying on a single test, helping guide subsequent management decisions.
These evaluations provide complementary evidence. Imaging examines the lesion and surrounding anatomy, laboratory tests add measurable clinical findings, and tissue sampling helps characterize the growth directly. Interpreting them together supports a more complete assessment of extent and stage. That combined picture can inform whether the clinical plan emphasizes surgery, systemic therapy, or palliative care.
Treatment selection follows characterization and staging rather than a one-size-fits-all pathway. Pancreaticoduodenectomy, also called the Whipple procedure, is one possible surgical approach, while systemic therapy addresses treatment through the body. Palliative care is another option when management centers on supportive goals. These choices reflect the tumor’s findings and the overall clinical situation.