Pancreaticoduodenectomy Complications

Pancreaticoduodenectomy complications are adverse events that can arise during recovery from the Whipple procedure, a complex operation used to treat diseases of the pancreatic head, bile duct, and duodenum. Because surgery requires resection followed by reconstruction of the pancreatic, biliary, and gastrointestinal pathways, problems may develop at the surgical anastomoses or in surrounding organs. Important complications include postoperative pancreatic fistula, delayed gastric emptying, bile leakage, hemorrhage, infection, and impaired wound healing. Recognizing their mechanisms, risk factors, and clinical signs supports timely diagnosis and treatment, improves postoperative management, and helps researchers evaluate surgical techniques and patient outcomes.

Pancreaticoduodenectomy Complications - Related Videos

Research

JoVE Journal - Medicine

Technical Detail for Robot Assisted Pancreaticoduodenectomy

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Cited by 9 •

2019

The following manuscript details a stepwise approach to the robot-assisted pancreaticoduodenectomy performed at the University of Pittsburgh Medical Center.

Modified Single-Loop Reconstruction for Pancreaticoduodenectomy

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Cited by 2 •

2019

The technique of modified single-loop reconstruction following pancreaticoduodenectomy separates pancreatic secretion from bile, thus reducing the severity of POPF without prolonging the duration of surgery.

Research

JoVE Journal - Cancer Research
Free Sample

Application of Simplified Stent-bridging Pancreaticogastrostomy in Open Pancreaticoduodenectomy

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2026

Here, we present the stent-bridging pancreaticogastrostomy (PG) technique, which uses a stent to bridge the remnant pancreas to the stomach during open pancreaticoduodenectomy. The stent-bridging PG aims to simplify the anastomosis, achieve complete diversion of pancreatic juice, and minimize manipulation of the pancreatic remnant.

Management of the Uncinate Process in No-Touch Laparoscopic Pancreaticoduodenectomy

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Cited by 2 •

2023

Complete resection of the uncinate process and mesopancreas is one of the most important and difficult processes in laparoscopic pancreatoduodenectomy (LPD). This article presents a method for managing the uncinate process in no-touch LPD using the median-anterior and left-posterior approaches to the superior mesenteric artery (SMA).

Education

JoVE Core - Pathophysiology

Healing II: Complications

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2026

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

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