Endometriosis Diagnosis
Endometriosis Diagnosis - Related Videos
07:12
A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice
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Cited by 2 •
2020
Many rodent models of endometriosis are limited by technical complexity, reproducibility, and/or need for immunocompromised animals or special reporter mice. We present a simplified system of lesion induction using any experimental mouse with an independently verifiable, objective scoring system and with no requirement for ovariectomy or survival surgery.
07:20
Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
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Cited by 21 •
2012
Loss of peritoneal integrity provides a new paradigm to understand and treat chronic pelvic pain in women with mild forms of endometriosis and can be easily detected using intraoperative instillation of dye at the time of laparoscopy.
08:02
Mouse Model of Surgically-induced Endometriosis by Auto-transplantation of Uterine Tissue
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Cited by 63 •
2012
A description of the surgical induction of endometriosis in mice and rats by auto-transplantation of uterine tissue to the arterial cascade of the intestinal mesentery.
08:16
Noninvasive Monitoring of Lesion Size in a Heterologous Mouse Model of Endometriosis
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Cited by 12 •
2019
Here, we present a protocol for live-imaging of fluorescently labeled human endometrial fragments grafted in mice. The method allows studying the effects of drugs of choice on endometriotic lesion size through monitoring and quantification of fluorescence emitted by the fluorescent reporter on real...
07:34
FISH for Pre-implantation Genetic Diagnosis
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Cited by 17 •
2011
This article describes the selection of suitable probes for single-cell FISH, spreading techniques for blastomere nuclei, and in situ hybridization and signal scoring, applied to pre-implantation genetic diagnosis (PGD) in a clinical setting.
FAQs
The process begins by characterizing symptoms and reviewing the medical history, especially pelvic pain and fertility concerns. A pelvic examination then adds information about possible anatomical changes that may support suspicion of disease. Because these findings can overlap with other causes of pelvic pain, clinicians use them together rather than treating any single symptom or examination result as definitive.
Transvaginal ultrasound and magnetic resonance imaging help identify structural findings associated with endometriosis, including lesions, ovarian endometriomas, and related anatomical changes. Imaging can therefore strengthen or refine the clinical assessment without relying only on symptoms. The results also help determine whether further evaluation is needed when the suspected disease remains uncertain.
Laparoscopy allows clinicians to directly visualize areas where endometriotic lesions are suspected, providing information that history, examination, and imaging may not establish clearly. When tissue is assessed, histological analysis may support confirmation. This combination is particularly relevant when noninvasive findings do not resolve diagnostic uncertainty and a more direct evaluation is needed.
Evaluation generally progresses from medical history and symptom assessment to pelvic examination, followed by imaging when appropriate. Transvaginal ultrasound or magnetic resonance imaging can assess suspected lesions and anatomical changes. If uncertainty persists, laparoscopy may provide direct visualization, and histological analysis may add supporting evidence. This staged approach combines clinical, imaging, and procedural information.
A clearer diagnosis helps clinicians distinguish endometriosis from other potential causes of pelvic pain and organize management around the patient’s concerns. The findings can inform care related to pain, fertility, and possible disease progression. Diagnosis is therefore not limited to naming the condition; it also provides a basis for selecting an appropriate management strategy.
Accurate evaluation can clarify whether suspected endometriosis is contributing to pelvic pain, infertility, or other symptoms. It may also identify ovarian endometriomas or related anatomical changes that affect clinical planning. By establishing a more informed picture of the condition, the diagnostic process supports timely management and helps address both immediate symptoms and fertility-related concerns.