Permanent Suture

Permanent suture is a nonabsorbable surgical material used to approximate tissue and maintain wound support over extended periods, making it important when healing tissues require lasting mechanical reinforcement. Made from materials such as polypropylene, nylon, polyester, or stainless steel, it holds wound edges together through continuous tensile strength while the surrounding tissue heals; because it remains in the body, it can also provoke a localized foreign-body response. Permanent sutures are selected for skin closure, vascular and cardiovascular repair, tendon reconstruction, and reinforcement of fascia or hernia repairs. Their material properties, handling, and tissue compatibility influence healing, infection risk, and long-term surgical outcomes.

Permanent Suture - Related Videos

Research

JoVE Journal - Medicine

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

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Cited by 16 •

2013

We describe a highly reproducible method for the permanent occlusion of a rodent major cerebral blood vessel. This technique can be accomplished with very little peripheral damage, minimal blood loss, a high rate of long-term survival, and consistent infarct volume commensurate with the human clinical population.

The Application Of Permanent Middle Cerebral Artery Ligation in the Mouse

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Cited by 29 •

2011

Middle cerebral artery (MCA) ligation is a technique to study focal cerebral ischemia in animal models. In this method, the middle cerebral artery is exposed by craniotomy and ligated by cauterization. This method gives highly reproducible infarct volumes and increased post-operative survival rates compared to other methods available.

Q Suture Technique: A Suturing Technique to Reduce Gap Formation and Increase Tensile Strength in Tendon Repair

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2025

In this video, we demonstrate suturing techniques — core suture and Q suture — to repair the foot flexor tendon in an ex vivo porcine model. Q sutures enhance the strength of the core suture in tendon repair and decrease gapping at the tendon repair site.

Research

JoVE Journal - Neuroscience
Free Sample

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

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Cited by 17 •

2017

A protocol for stroke onset time estimation in a rat model of stroke exploiting quantitative magnetic resonance imaging (qMRI) parameters is described. The procedure exploits diffusion MRI for delineation of the acute stroke lesion and quantitative T1 and T2 (qT1 and qT2) relaxation times for timing of stroke.

Education

JoVE Business - Macroeconomics

Permanent Income Hypothesis

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2025

The Permanent Income Hypothesis (PIH), formulated by economist Milton Friedman, explains how individuals plan their consumption based on long-term income expectations rather than current earnings. This theory is fundamental for analyzing consumer behavior over time.Friedman separated total income into two parts: permanent income and transitory income.Permanent income represents the average income individuals expect throughout their lives, accounting for predictable and stable...

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