Proton Magnetic Resonance

Proton magnetic resonance is the interaction of hydrogen nuclei with a magnetic field and radiofrequency energy, a principle that underlies major diagnostic tools in medicine. In a strong magnetic field, proton spins partially align; radiofrequency pulses disturb this alignment, and the nuclei release energy as they relax, producing signals that can be spatially encoded with magnetic field gradients. These signals form the basis of magnetic resonance imaging, which provides detailed views of soft tissues without ionizing radiation, and magnetic resonance spectroscopy, which measures selected biochemical compounds. Proton magnetic resonance supports diagnosis, treatment planning, and research into tissue structure and metabolism.

Proton Magnetic Resonance - Related Videos

Education

JoVE Science Education - Chemistry

Nuclear Magnetic Resonance (NMR) Spectroscopy

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2023

Source: Laboratory of Dr. Henrik Sundén – Chalmers University of Technology Nuclear magnetic resonance (NMR) spectroscopy is a vital analysis technique for organic chemists. With the help of NMR, the work in the organic lab has been facilitated tremendously. Not only can it provide information about the structure of a molecule but also determine the content and purity of a sample. Compared with other commonly encountered techniques for organic chemists — such as thermal analysis and mass...

Cardiac Magnetic Resonance Imaging

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2023

Source: Frederick W. Damen and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana In this video, high field, small-bore magnetic resonance imaging (MRI) with physiological monitoring is demonstrated to acquire gated cine loops of the murine cardiovascular system. This procedure provides a basis for assessing left-ventricular function, visualizing vascular networks, and quantifying motion of organs due to respiration. Comparable small animal...

Research

JoVE EoE - Spectroscopy Techniques

Nuclear Magnetic Resonance Spectroscopy to Identify Multiple Phosphorylations in Proteins

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2025

This video demonstrates the use of nuclear magnetic resonance spectroscopy (NMR) techniques to identify multiple phosphorylations in a protein. The phosphorylation of a protein at specific amino acid causes the deshielding of the neighboring amide hydrogen, which generates the spectral difference.

Time-of-Flight Magnetic Resonance Angiography to Visualize Blood Vasculature

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2025

Position the patient's head inside the radiofrequency, or RF, coil of a magnetic resonance imaging, or MRI, machine.Initiate the time-of-flight magnetic resonance angiography or TOF MRA, a non-invasive technique for visualizing blood vessels.Select a tissue slice for imaging to visualize arteries and veins.Apply an RF pulse to excite the protons within the selected imaging slice. These protons release energy, which is detected as an MR signal.Repeated application of RF pulses saturates the MR...

The Use of Magnetic Resonance Spectroscopy as a Tool for the Measurement of Bi-hemispheric Transcranial Electric Stimulation Effects on Primary Motor Cortex Metabolism

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Cited by 30 •

2014

This article aims to describe a basic protocol for combining transcranial direct current stimulation (tDCS) with proton magnetic resonance spectroscopy (1H-MRS) measurements to investigate the effects of bilateral stimulation on primary motor cortex metabolism.

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