Rodent Ultrasound
Rodent Ultrasound - Related Videos
10:36
Ultrasound Localization Microscopy for Super-Resolution Mapping of the Rodent Brain Microvasculature
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2025
Ultrasound Localization Microscopy (ULM) is a recently developed technique that allows for an unprecedented level of resolution in imaging the microvasculature in vivo. In this work, we describe in detail how to obtain super-resolved images of the brain microvasculature in rodents using a standardized functional ultrasound imaging platform designed for preclinical research.
09:00
Murine Echocardiography and Ultrasound Imaging
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Cited by 61 •
2010
This video demonstrates use of a rail-mounted high-frequency ultrasound probe to perform echocardiography on an anesthetized mouse. The methods describe both conventional two-dimensional and M-mode measurements of cardiac function in addition to newer, more powerful tools such as color Doppler, strain analysis, as well as general and targeted contrast imaging.
14:20
High-frequency Ultrasound Imaging of the Abdominal Aorta
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2023
Source: Amelia R. Adelsperger, Evan H. Phillips, and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana High-frequency ultrasound systems are used to acquire high resolution images. Here, the use of a state-of-the-art system will be demonstrated to image the morphology and hemodynamics of small pulsatile arteries and veins found in mice and rats. Ultrasound is a relatively inexpensive, portable, and versatile method for the noninvasive...
09:40
Hemodynamic Characterization of Rodent Models of Pulmonary Arterial Hypertension
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Cited by 35 •
2016
Pulmonary arterial hypertension (PAH) is a disease of pulmonary arterioles that leads to their obliteration and the development of right ventricular failure. Rodent models of PAH are critical in understanding the pathophysiology of PAH. Here we demonstrate hemodynamic characterization, with right heart catheterization and echocardiography, in the mouse and rat.
14:12
Rodent Identification II
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2015
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN Animal records must be accurately maintained to ensure that data collection is correct. Records range from maintaining information on cage cards to having a detailed database with all of the relevant information on each animal. The primary component of recordkeeping is the individual identification of research animals. There are a variety of methods suitable for identifying mice and rats. This...
FAQs
Image formation depends on differences at tissue boundaries: each boundary can return echoes after acoustic pulses enter the body. The transducer receives those echoes, and the system converts them into a real-time representation of internal structures. This mechanism allows investigators to follow anatomical changes during repeated examinations rather than relying on a single endpoint.
Doppler methods add a functional dimension by assessing blood flow rather than showing anatomy alone. In rodent studies, this capability is especially relevant when investigators evaluate cardiovascular function or observe how a disease or treatment affects circulation. The same imaging approach can therefore support both structural and flow-related observations.
The absence of ionizing radiation makes serial imaging practical for studies that repeatedly monitor the same animal. This design lets researchers compare disease progression or therapeutic response over time within an individual, rather than relying only on differences between separate animals. It can therefore improve measurement continuity while supporting reduction in animal use.
A basic examination requires a transducer and coupling gel. The gel provides the acoustic interface needed for pulses to pass between the transducer and the body. The operator then uses the transducer to send pulses and receive returning echoes, producing images that can be reviewed in real time. This setup supports imaging of internal structures without ionizing radiation.
Researchers can apply rodent ultrasound across several preclinical questions, including pregnancy monitoring, organ anatomy, tumor assessment, cardiovascular evaluation, and treatment response. The method is particularly useful when investigators need measurements from living animals at multiple time points. Its broad range of targets makes it relevant to both disease characterization and therapy studies.
In medical research, the technique connects imaging findings with preclinical evaluation by allowing researchers to observe anatomy, follow progression, and assess whether treatment responses change over time. Because examinations can be repeated without ionizing radiation, rodent models provide longitudinal information while investigators study disease and interventions. This supports assessment of therapeutic effects in small-animal studies.