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Chapters
- 00:05Title
- 00:43Echocardiography
- 02:48Right Heart Catheterization
- 04:45Open-chest Right Ventricle Pressure-volume Loop Analysis
- 06:24Heart and Lung Sample Collection
- 07:58Results: Representative Pulmonary Arterial Hypertension Data in Rodent Models
- 08:49Conclusion
Pulmonary arterial hypertension (PAH) is a disease of pulmonary arterioles that leads to their obliteration and the development of right ventricular failure. Rodent models of PAH are critical in understanding the pathophysiology of PAH. Here we demonstrate hemodynamic characterization, with right heart catheterization and echocardiography, in the mouse and rat.
