Splenic Vein Cannulation

Splenic vein cannulation is a technique that places a catheter into the splenic vein to obtain direct venous access to blood draining the spleen, an important approach for studying splenic and portal circulation. Access is established by introducing the catheter into the vessel under surgical or image-guided conditions, allowing blood sampling, pressure measurement, or delivery of agents while maintaining controlled vascular access. In medicine and biomedical research, the technique supports investigation of portal hemodynamics, splenic function, and substances released by the spleen, and may assist evaluation of disorders such as portal hypertension. Its value depends on careful guidance and management of bleeding and vascular complications.

Splenic Vein Cannulation - Related Videos

Education

JoVE Science Education - Clinical Skills

Peripheral Venous Cannulation

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2023

Source: Sharon Bord, MD, Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA Placement of an intravenous (IV) catheter is one of the key procedures in medicine. The IV catheter allows patients to receive critical medications, including pain medicine, insulin, antibiotics, blood products, and fluids for rehydration. Additionally, placing an IV catheter allows for blood samples to be obtained, which can be sent to the laboratory for testing and...

Research

JoVE Journal - Medicine

Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection

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2025

We present a laparoscopic technique for anatomic S7+S8d resection with right hepatic vein transection, preserving the inferior right hepatic vein and segment S6. Relying on meticulous anatomical landmarks without intraoperative ultrasound, this approach offers a precise and parenchyma-sparing option for dorsally located right-liver tumors, particularly in settings with limited advanced navigation resources.

Intraduodenal Cannulation in a Rat Model for Immunopathology Studies

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2025

This video demonstrates intraduodenal cannulation in a rat model. After anesthetizing the rat, the duodenum is located and a small puncture is created. A J-shaped cannula with a beveled tip is carefully inserted and secured, and the incision is closed. The cannulated rat model enables intra-intestinal infusion for immunopathology studies.

Cannulation of the Mouse Submandibular Salivary Gland via the Wharton's Duct

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Cited by 17 •

2011

A protocol for the cannulation of the mouse submandibular salivary gland via the Wharton's duct is described. For this experiment, the trypan blue solution is used as a dyer to demonstrate how this technique effectively delivers infusions into the targeted gland, and to suggest the reliability of this new approach as a potential clinical drug/cell therapy for the regeneration of salivary glands.

Cannulation of the Carotid Artery in a Rat Model

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2025

In this video, we demonstrate a surgical procedure to cannulate the left carotid artery in a rat model.

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