Dura Mater Removal

Dura mater removal is a neurosurgical technique in which the tough outer meningeal layer surrounding the brain is opened or excised to provide access to underlying neural tissue. After the skull is opened, the dura mater is carefully incised, reflected, or removed while controlling bleeding and protecting the exposed cortex. In neuroscience, this approach enables procedures such as cortical recording, stimulation, targeted injections, tissue sampling, and treatment of lesions. Because the dura contributes to mechanical protection and separates the brain from surrounding tissues, its removal requires precise handling and closure to limit injury, fluid leakage, and infection.

Dura Mater Removal - Related Videos

Research

JoVE EoE - Neuroimaging

Investigating the Origins of Sensory Neurons in the Dura Mater Using Fluorescence Microscopy

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2025

Source: Wang, J., et al. Visualizing the Calcitonin Gene-Related Peptide Immunoreactive Innervation of the Rat Cranial Dura Mater with Immunofluorescence and Neural Tracing. J. Vis. Exp. (2021). This video demonstrates a method to trace the origins of sensory neurons in the dura mater using fluorescence microscopy. A retrograde tracer is introduced into the exposed dura mater of an anesthetized rat. The tracer is taken up by sensory neuronal axons and travels retrogradely to their cell bodies...

Visualizing the Calcitonin Gene-Related Peptide Immunoreactive Innervation of the Rat Cranial Dura Mater with Immunofluorescence and Neural Tracing

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Cited by 3 •

2021

Here we present a protocol to visualize spatial correlation of calcitonin gene-related peptide (CGRP)-immunoreactive nerve fibers and blood vessels in the cranial dura mater using immunofluorescence and fluorescent histochemistry with CGRP and phalloidin, respectively. In addition, the origin of these nerve fibers was retrograde traced with a fluorescent neural tracer.

Minimally Invasive Endoscopic Procedure for Hematoma Removal from the Human Brain

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2025

Source: Pan, J. et. al., Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation. J. Vis. Exp. (2021)This video demonstrates minimally invasive endoscopic hematoma removal, using a navigation-guided sheath and endoscopic aspiration with saline irrigation to preserve brain structure.

Exposure of the Pig CNS for Histological Analysis: A Manual for Decapitation, Skull Opening, and Brain Removal

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Cited by 26 •

2017

The goal of this paper and instructional video is to describe how to expose and remove the postmortem pig brain and pituitary gland in an intact state, suitable for subsequent macroscopic and histological analysis.

Education

JoVE Science Education - Chemistry

Rotary Evaporation to Remove Solvent

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2023

Source: Dr. Melanie Pribisko Yen and Grace Tang — California Institute of Technology Rotary evaporation is a technique most commonly used in organic chemistry to remove a solvent from a higher-boiling point compound of interest. The rotary evaporator, or "rotovap", was invented in 1950 by the chemist Lyman C. Craig. The primary use of a rotovap is to dry and purify samples for downstream applications. Its speed and ability to handle large volumes of solvent make rotary evaporation a preferred...

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