Early Auditory Cortex

Early auditory cortex refers to the first cortical stages of auditory processing, where the brain begins transforming sound signals into neural representations of frequency, timing, and intensity. Located primarily in and around primary auditory cortex, these regions receive organized input from the medial geniculate nucleus of the thalamus and preserve a tonotopic arrangement, allowing neighboring neurons to respond preferentially to different sound frequencies. Studying early auditory cortex helps explain how acoustic features are encoded before higher cortical areas interpret speech, music, and meaningful environmental sounds. This work informs research on sensory processing, hearing loss, auditory perception, and neurological disorders affecting sound recognition.

Early Auditory Cortex - Related Videos

Research

JoVE EoE - Neuroimaging

Measuring Cerebral Blood Volume in the Auditory Cortex Using Vascular Space Occupancy

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2025

Position a human participant’s head within the head coil of a functional magnetic resonance imaging, or fMRI, system.Employ vascular space occupancy or VASO, a technique to measure changes in cerebral blood volume, or CBV, the blood volume within the brain.Begin by applying an inversion recovery pulse to suppress signals from blood, allowing only signals from the surrounding tissue within the region to be detected.Next, use MRI-compatible earbuds to deliver auditory stimuli.The stimuli reach...

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI

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Cited by 6 •

2014

Functional studies of the auditory system in mammals have traditionally been conducted using spatially-focused techniques such as electrophysiological recordings. The following protocol describes a method of visualizing large-scale patterns of evoked hemodynamic activity in the cat auditory cortex using functional magnetic resonance imaging.

A Stereotactically Guided Ablation Technique for Auditory Cortex Removal in Rats

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2025

This video demonstrates a stereotactically-guided surgical procedure for ablating the auditory cortex in a rat. The steps include identifying anatomical landmarks in an anesthetized rat secured in a stereotactic frame, creating a window on the skull above the auditory cortex, aspirating the cortical layers, and providing post-operative care to assess the impact of the ablation on sound processing.

Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging

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Cited by 13 •

2012

Auditory processing is the basis of speech and music-related processing. Transcranial Magnetic Stimulation (TMS) has been used successfully to study cognitive, sensory and motor systems but has rarely been applied to audition. Here we investigated TMS combined with functional Magnetic Resonance Imaging to understand the functional organization of auditory cortex.

Research

JoVE Journal - Behavior
Free Sample

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain

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Cited by 10 •

2017

We describe a method for the stereotactically-guided location, exposure, and ablation of the auditory cortex in rats. The localization of the ablation is assessed using a coordinate map postmortem.

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