Pupil Corneal Reflection

Pupil corneal reflection is an optical eye-tracking method that estimates gaze direction from the relative positions of the pupil and a reflected light image on the cornea. Infrared illumination produces a small corneal reflection, or glint, while a camera records the pupil and glint; the measured geometry changes with eye rotation and can be calibrated to map gaze onto a visual scene. In neuroscience, pupil corneal reflection supports noninvasive measurement of visual attention, oculomotor control, and perception, enabling eye-tracking experiments in behavioral research, human-computer interaction, and clinical assessment.

Pupil Corneal Reflection - Related Videos

Research

JoVE Journal - Medicine

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse

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Cited by 75 •

2014

Neovascularization (NV) of the cornea can complicate multiple visual pathologies. Utilizing a controlled, alkali-burn injury model, a quantifiable level of corneal NV can be produced for mechanistic study of corneal NV and evaluation of potential therapies for neovascular disorders.

Education

JoVE Science Education - Physics

Reflection and Refraction

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2023

Source: Derek Wilson, Asantha Cooray, PhD, Department of Physics & Astronomy, School of Physical Sciences, University of California, Irvine, CA Light travels at different speeds depending on the material through which it is propagating. When light travels from one material to another, it will either slow down or speed up. In order to conserve energy and momentum, the light must change the direction in which it propagates. This bending of light is known as refraction. Some fraction of the...

Interference Reflection Microscopy for Label-Free Visualization of Microtubule Dynamics

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2025

In this video, we describe the interference reflection microscopy (IRM) technique to visualize microtubules growing on a coverslip surface in the presence of a suitable buffer. Upon illumination with incident light, the coverslip-buffer interface and buffer-microtubule interface reflect light, which combines to create an interference pattern, enabling the visualization of microtubules as high-contrast images against a bright background.

Research

JoVE Journal - Medicine
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Corneal Donor Tissue Preparation for Endothelial Keratoplasty

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Cited by 31 •

2012

Endothelial corneal transplantation is a surgical technique for treatment of posterior corneal diseases. Mechanical microkeratome dissection to prepare tissue results in thinner, more symmetric grafts with less endothelial cell loss and improved outcomes. Dissections can be performed at the eye bank prior to corneal transplantation surgery.

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

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Cited by 155 •

2011

Corneal Confocal microscopy is a non-invasive clinical technique which may be used to quantify C fibre damage to diagnose and stratify patients with increasing neuropathic severity.

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