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Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
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JoVE Journal Medicine
Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

DOI:
10.3791/2194-v

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11:29 min

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January 03, 2011

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,
1Division of Cardiovascular Medicine,University of Manchester

Chapters

  • 00:05Title
  • 00:57Introduction
  • 02:25Preparing the Camera
  • 03:45Preparing the Patient and Aligning the Camera
  • 05:51Examining the Patient
  • 07:54Analyzing an Examination
  • 10:46Conclusion

Summary

Automatic Translation

Automatic Translation

Corneal Confocal microscopy is a non-invasive clinical technique which may be used to quantify C fibre damage to diagnose and stratify patients with increasing neuropathic severity.

Tags

Corneal Confocal MicroscopyPeripheral NeuropathiesSmall Fibre PathologyNon-invasive TechniqueQuantifyAccurate QuantificationAt Risk PatientsDeteriorationNew TherapiesConventional MethodsNeurological DeficitsElectrophysiologyQuantitative Sensory TestingFunctional AlterationsNeuropathySmall FibresLarge Fibre DysfunctionRegeneration And RepairSural Nerve BiopsyElectron MicroscopySkin-Punch BiopsyInvasive ProceduresLengthy Laboratory ProceduresExpertiseIn-vivo ImagingCorneal Nerve FibresEarly Nerve DamageLoss Of Intraepidermal Nerve FibresSkin BiopsiesStratification Of Neuropathic SeverityPancreas TransplantationDiabetic PatientsIdiopathic Small Fibre NeuropathyFabry’s Disease

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