Stimulation Device

A stimulation device is an instrument that applies controlled electrical, magnetic, optical, or chemical signals to influence the activity of excitable cells, including neurons. In neuroscience, these devices deliver precisely timed and localized stimuli that alter membrane potentials, trigger or suppress action potentials, or modulate communication within neural circuits. Researchers use stimulation devices to investigate brain and spinal cord function, map connections, and evaluate how neural networks generate behavior. Clinically, related technologies support treatments for neurological disorders by adjusting abnormal circuit activity, while advances in targeting and closed-loop control continue to improve experimental precision and therapeutic potential.

Stimulation Device - Related Videos

Research

JoVE EoE - Large Animal Models

Automated Periodic Stimulation Electrode Installation: A Technique to Surgically Implant An Automated Stimulation Device on the Vagus Nerve in a Porcine Model

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2025

In this video, we demonstrate the procedure for the installation of an automated periodic stimulation electrode on the vagus nerve for monitoring nerves during thyroid surgeries in a porcine model. This helps in the correct identification of the target nerve during surgical procedures.

Combining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network

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Cited by 17 •

2010

In this article, we examine the methodology and considerations relevant to the combination of TMS and fMRI to examine the effects of brain stimulation on the default network.

Research

JoVE Journal - Neuroscience
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The NeuroStar TMS Device: Conducting the FDA Approved Protocol for Treatment of Depression

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Cited by 83 •

2010

In this article, we examine the methodology and considerations relevant to the FDA approved depression treatment protocol using the Neuronetics NeuroStar TMS device.

Electric and Magnetic Field Devices for Stimulation of Biological Tissues

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2021

This protocol describes the step-by-step process to build both electrical and magnetic stimulators used to stimulate biological tissues. The protocol includes a guideline to simulate computationally electric and magnetic fields and manufacture of stimulator devices.

Using a Microfluidics Device for Mechanical Stimulation and High Resolution Imaging of C. elegans

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Cited by 18 •

2018

New tools for mechanobiology research are needed to understand how mechanical stress activates biochemical pathways and elicits biological responses. Here, we showcase a new method for selective mechanical stimulation of immobilized animals with a microfluidic trap allowing high-resolution imaging of cellular responses.

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