Engineering Mechanics
Engineering Mechanics - Related Videos
08:04
Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering
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Cited by 24 •
2013
We designed a novel mechanical loading bioreactor that can apply uniaxial or biaxial mechanical strain to a cartilage biocomposite prior to transplantation into an articular cartilage defect.
11:51
Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy
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Cited by 16 •
2016
This manuscript describes the creation of defined engineered cardiac tissues using surface marker expression and cell sorting. The defined tissues can then be used in a multi-tissue bioreactor to investigate mechanisms of cardiac cell therapy in order to provide a functional, yet controlled, model system of the human heart.
12:18
Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
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Cited by 16 •
2012
The procedure demonstrates the methodology of magnetic resonance elastography for monitoring the engineered outcome of adipose and osteogenic tissue engineered constructs through noninvasive local assessment of the mechanical properties using microscopic magnetic resonance elastography (μMRE).
08:52
Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
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Cited by 19 •
2018
We showcase the development of self-assembled, three-dimensional bundles of longitudinally aligned astrocytic somata and processes within a novel biomaterial encasement. These engineered "living scaffolds", exhibiting micron-scale diameter yet extending centimeters in length, may serve as test-beds to study neurodevelopmental mechanisms or facilitate neuroregeneration by directing neuronal migration and/or axonal pathfinding.
16:41
Experimental Approaches to Tissue Engineering
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Cited by 2 •
2007
FAQs
The distinction depends on whether the analysis concerns bodies in equilibrium or bodies whose motion changes under loading. Static analysis emphasizes force and moment balances, while dynamic analysis considers motion alongside applied forces. This separation helps engineers select appropriate models for structures, machines, and other systems, then predict reactions, stresses, displacement, or motion under the relevant operating conditions.
A free-body diagram isolates a body or component and represents the forces acting on it, making the intended force and moment balances explicit. This organized view supports calculation of reactions and helps connect applied loading to equilibrium, motion, or deformation. Engineers can therefore examine individual parts of a larger structure or machine before interpreting the complete system.
Moments describe the turning effect of forces about a selected point or axis, so they complement direct force balances in equilibrium analysis. A body may experience forces whose combined effects tend to rotate it even when their net force is considered separately. Including moment balances helps determine reactions and assess whether structures or machine components remain stable under applied loading.
Material principles provide the link between external loading and the internal response of a body. After forces and moments are identified, analysis can be used to predict stresses, displacement, deformation, and possible failure. This connection matters because a design must not only balance applied loads, but also maintain acceptable behavior in the material and component during operation.
An analysis commonly begins by identifying the body, loading condition, and relevant constraints. Engineers then construct free-body diagrams, apply force and moment balances, and use material principles to evaluate stresses, reactions, displacement, stability, or failure. The resulting predictions can be compared with experimental testing or computational simulation, linking theoretical calculations to evidence about actual performance.
The methods support design and evaluation of bridges, vehicles, buildings, robotic systems, and mechanical components. Depending on the system and loading condition, analysis can predict reactions, stresses, displacement, stability, motion, and failure before construction or operation. This advance assessment helps engineers improve safety and efficiency while connecting fundamental scientific laws with practical design decisions.