Von Mises Criterion

The von Mises criterion is a failure theory used to predict yielding in ductile materials subjected to complex, multiaxial stress states. It converts the combined normal and shear stresses at a point into an equivalent von Mises stress, based on the distortion energy associated with shape change, and compares this value with the material’s yield strength. In engineering design, the criterion supports analysis of components such as pressure vessels, shafts, frames, and machine parts under tension, compression, torsion, or combined loading. It is widely implemented in finite element analysis to identify regions likely to yield and assess structural safety.

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Research

JoVE Journal - Medicine

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

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Cited by 6 •

2017

In this paper, we describe a method to assess endothelial von Willebrand factor release and the subsequent platelet capture under fluid shear stress in response to inflammatory stimuli using an in vitro flow chamber system.

Education

JoVE Core - Electrical Engineering

Routh-Hurwitz Criterion I

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2024

Consider an electrical power grid, where stability is essential to prevent blackouts. The Routh-Hurwitz criterion is a valuable tool for assessing system stability under varying load conditions or faults. By analyzing the closed-loop transfer function, the Routh-Hurwitz criterion helps determine whether the system remains stable. To apply the Routh-Hurwitz criterion, a Routh table is constructed. The table's rows are labeled with powers of the complex frequency variable s, starting from the...

Routh-Hurwitz Criterion II

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2025

In the application of the Routh-Hurwitz criterion, two specific scenarios can arise that complicate stability analysis. The first scenario occurs when a singular zero appears in the first column of the Routh table. This situation creates a division by zero issues. To resolve this, a small positive or negative number, denoted as epsilon (∈), is substituted for the zero. The stability analysis proceeds by assuming a sign for ∈. If ∈ is positive, any sign change in the first column of the Routh...

Pharmacokinetic Models: Comparison and Selection Criterion

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2025

Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play. Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.

Potential-Energy Criterion for Equilibrium

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2023

Potential energy or potential function plays an essential role in determining the stability of a mechanical system. If a system is subjected to both gravitational and elastic forces, the potential function of the system can be expressed as the algebraic sum of gravitational and elastic potential energy. If the system is in equilibrium and is displaced by a small amount, then the work done on the system equals the negative of the change in the system's potential energy from the initial to the...

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