Functional Analysis

Functional analysis is a branch of mathematics that studies infinite-dimensional vector spaces and the functions, operators, and transformations defined on them. It uses structures such as norms, inner products, convergence, and spectral properties to analyze how complex systems behave, often by converting relationships into equations that can be studied rigorously. In immunology and infection research, these tools support mathematical modeling of pathogen transmission, immune-cell interactions, inflammatory responses, and treatment dynamics. Functional analysis can help establish whether models have solutions, determine their stability, and identify patterns that improve interpretation of experimental data and prediction of disease outcomes.

Functional Analysis - Related Videos

Research

JoVE Journal - Neuroscience

3D Kinematic Analysis for the Functional Evaluation in the Rat Model of Sciatic Nerve Crush Injury

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Cited by 5 •

2020

We introduce a kinematic analysis method that uses a three-dimensional motion capture apparatus containing four cameras and data processing software for performing functional evaluations during fundamental research involving rodent models.

Functional Analysis of the Larval Feeding Circuit in Drosophila

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Cited by 22 •

2013

The feeding circuit in Drosophila melanogaster larvae serves a simple yet powerful model that allows changes in feeding rate to be correlated with alterations in the stomatogastric neural circuitry. This circuit is composed of central serotonergic neurons that send projections to the mouth hooks as well as the foregut.

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

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Cited by 17 •

2012

We describe a novel approach for simultaneous analysis of brain function and structure using magnetic resonance imaging (MRI). We assess brain structure with high-resolution diffusion-weighted imaging and white-matter fiber tractography. Unlike standard structural MRI, these techniques allow us to directly relate anatomical connectivity to functional properties of brain networks.

In Vitro Analysis of E3 Ubiquitin Ligase Function

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Cited by 8 •

2021

The present study provides detailed in vitro ubiquitylation assay protocols for the analysis of E3 ubiquitin ligase catalytic activity. Recombinant proteins were expressed using prokaryotic systems such as Escherichia coli culture.

Research

JoVE Journal - Biology
Free Sample

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

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Cited by 43 •

2014

The zebrafish adult kidney is an excellent system for renal regeneration and disease studies. An essential aspect of such research is the assessment of nephron structure and function. This protocol describes several methodologies that can be implemented to assess nephron tubule composition and to evaluate renal reabsorption.

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