Abdominal Aortic Stent
Abdominal Aortic Stent - Related Videos
06:45
Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
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Cited by 44 •
2010
The Colon Ascendens Stent Peritonitis (CASP) is a highly standardized model for polymicrobial abdominal sepsis in rodents. This article describes the surgical procedure of CASP. The CASP model and its variants allow the systematic investigation of various problems concerning the subject of sepsis.
10:12
Near-infrared Fluorescence Imaging of Abdominal Aortic Aneurysms
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2023
Source: Arvin H. Soepriatna1, Kelsey A. Bullens2, and Craig J. Goergen1 1 Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 2 Department of Biochemistry, Purdue University, West Lafayette, Indiana Near-infrared fluorescence (NIRF) imaging is an exciting optical technique that utilizes fluorescent probes to visualize complex biomolecular assemblies in tissues. NIRF imaging has many advantages over conventional imaging methods for noninvasive imaging of diseases.
10:23
Creation of Murine Experimental Abdominal Aortic Aneurysms with Elastase
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Cited by 55 •
2009
This video shows how to induce abdominal aortic aneurysms (AAA) in mice via transient intraluminal infusion of porcine pancreatic elastase into the infrarenal segment of the abdominal aorta. The model has the ability to add broad insight into the pathobiology of AAA due to the emergence of numerous transgenic and gene knockout mice.
08:33
Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model
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Cited by 5 •
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Understanding the cellular and molecular mechanisms of re-endothelialization following arterial denudation injury is of paramount importance in preventing thrombosis and restenosis of arteries. Here we describe a protocol for reproducible arterial denudation injury of the infrarenal abdominal aorta. The procedure was developed to investigate the underlying mechanisms that regulate endothelial regeneration using mouse models.
05:37
Human Internal Mammary Artery (IMA) Transplantation and Stenting: A Human Model to Study the Development of In-Stent Restenosis
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Cited by 5 •
2012
This video shows a model to study the development of intimal hyperplasia after stent deployment using a human vessel (IMA) in an immunodeficient rat model.
FAQs
A stent-graft creates a sealed channel within the abdominal aorta, allowing blood to pass through the device rather than directly press against the aneurysm’s weakened wall. By redirecting flow across the affected segment, the treatment reduces pressure on that area. This mechanism is intended to lower the likelihood that the aneurysm will rupture.
Both devices can reinforce the aortic wall and help maintain blood flow, but they do so differently. A metal stent provides structural support, whereas a stent-graft also forms a sealed internal channel. That added seal allows the graft to divert blood away from an aneurysm rather than simply supporting the vessel segment.
Expansion places the compressed device against the targeted portion of the abdominal aorta, where it can provide support or establish the intended blood-flow pathway. Correct deployment is therefore central to the treatment’s mechanical effect. Imaging assists clinicians in positioning the device at the affected segment rather than relying on placement without visual guidance.
Imaging supports several stages of care: clinicians use it to select an appropriate device, guide positioning during deployment, and monitor the device afterward. These functions help confirm that the stent or stent-graft is located at the intended aortic segment and continues to support the treatment goal over time.
During an endovascular procedure, clinicians guide the compressed device through a catheter toward the affected segment of the abdominal aorta. They then expand it at the target location and use imaging to assist with placement. When a stent-graft is selected, deployment also establishes the sealed channel intended to divert blood around the aneurysm.
The principal clinical application described is treatment of an abdominal aortic aneurysm, a weakened area of the abdominal aorta. The device supports the vessel and, when configured as a stent-graft, redirects blood away from the aneurysm. The intended outcome is reduced pressure on the weakened wall and a lower risk of rupture.