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Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model
 

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

Article doi: 10.3791/54755
November 24th, 2016

Summary November 24th, 2016

Understanding the cellular and molecular mechanisms of re-endothelialization following arterial denudation injury is of paramount importance in preventing thrombosis and restenosis of arteries. Here we describe a protocol for reproducible arterial denudation injury of the infrarenal abdominal aorta. The procedure was developed to investigate the underlying mechanisms that regulate endothelial regeneration using mouse models.

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