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Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model
Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model
JoVE Journal
Medicine
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JoVE Journal Medicine
Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

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08:33 min

November 24, 2016

DOI:

08:33 min
November 24, 2016

9226 Views
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Summary

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Understanding the cellular and molecular mechanisms of re-endothelialization following arterial denudation injury is of paramount importance in preventing thrombosis and restenosis of arteries. Here we describe a protocol for reproducible arterial denudation injury of the infrarenal abdominal aorta. The procedure was developed to investigate the underlying mechanisms that regulate endothelial regeneration using mouse models.

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