Biomechanical Alterations

Biomechanical alterations are changes in the mechanical behavior, structure, or movement of biological tissues and body systems, often affecting health and physical function. They arise when forces, loads, motion, or tissue properties shift, disrupting normal relationships among muscles, bones, joints, connective tissues, and surrounding structures. In medicine, analyzing these changes through physical examination, motion assessment, imaging, and mechanical modeling helps identify disease-related dysfunction, injury, and impaired mobility. Biomechanical alterations also guide rehabilitation, prosthetic and orthotic design, surgical planning, and preventive care by linking mechanical causes to clinical outcomes and functional recovery.

Biomechanical Alterations - Related Videos

Research

JoVE EoE - Large Animal Models

In Vivo Biomechanical Testing of Nerve: A Procedure for Biomechanical Analysis of Brachial Plexus Nerve Injury in a Neonatal Pig Model

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2025

In this video, we demonstrate the biomechanical testing of the brachial plexus nerve in a pig model to measure the threshold tensile strength of the nerve when subjected to stretching. This technique helps in determining the structural and mechanical properties of the nerve.

Education

JoVE Core - Nursing

Alterations in Respiration II

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2024

There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients. In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes include...

Preparation of Rat Tail Tendons for Biomechanical and Mechanobiological Studies

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Cited by 21 •

2010

This article describes the experimental procedures used to prepare rat tail tendons for biomechanical and mechanobiological studies. Several features of the main steps in preparation are demonstrated, beginning with extraction, cross-sectional area measurement, rinsing and loading into the bioreactor chamber.

Altered States of Awareness

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2024

Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue. The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain that...

The Mammalian Ocular Lens in Focus: Development, Anatomy, Physiology, Transparency, Biomechanics, and Age-Related Challenges

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2026

The function of the ocular lens to focus light onto the retina depends on tissue transparency, biomechanics, and refractive index. This review highlights the three-dimensional architecture of the lens and discusses the complex mechanisms that maintain tissue homeostasis.

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