Noninvasive Intraocular Surgery

Noninvasive intraocular surgery refers to approaches that treat structures inside the eye without conventional surgical entry, aiming to reduce tissue disruption while addressing ocular disease. These procedures typically deliver focused energy through the eye’s external tissues, using controlled laser pulses or other precisely targeted modalities to alter, remove, or reshape selected structures while limiting damage to surrounding areas. In medicine, such techniques may support treatment planning and management of conditions involving the cornea, lens, retina, or other intraocular tissues. Their potential benefits include reduced surgical trauma, faster recovery, and improved procedural precision, although safety and effectiveness depend on the specific technology and clinical indication.

Noninvasive Intraocular Surgery - Related Videos

Research

JoVE EoE - Neuropathology

Induction of Elevated Intraocular Pressure in a Rat Model

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2025

Source: Lani-Louzada, R., et al., Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents. J. Vis. Exp. (2022)This video demonstrates the induction and monitoring of elevated intraocular pressure (IOP) in a rat model. The process involves cauterizing the limbal blood vessels, resulting in vessel occlusion and elevated IOP. The rat is then allowed to recover, and IOP is regularly monitored in both the experimental and control eyes for comparison.

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs

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Cited by 59 •

2016

Rabbits are widely used to study the pharmacokinetics of intraocular drugs. We describe a method for conducting pharmacokinetic studies of intraocular drugs using rabbit eyes.

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

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Cited by 1 •

2023

The present protocol describes removing residual epithelial cells by rotating the intraocular lens in extracapsular cataract surgery without extra tools for preventing posterior capsular opacification.

Education

JoVE Science Education - Engineering

Noninvasive Blood Pressure Measurement Techniques

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2023

Source: Hamna J. Qureshi and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana Here we will highlight the key similarities and differences of noninvasive blood pressure measurement techniques between humans and rodents and examine the engineering principles that govern blood pressure. The principles that govern current cuff technology to acquire systolic and diastolic pressures will also be discussed. Commercially available cuffs that connect...

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery

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2018

We describe a protocol to measure vortex formation time, an index of left ventricular filling efficiency, using standard transesophageal echocardiography techniques in patients undergoing cardiac surgery. We apply this technique to analyze vortex formation time in several groups of patients with differing cardiac pathologies.

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