Forelimb Hindlimb Coordination

Forelimb-hindlimb coordination is the neural control of movement that synchronizes the limbs during locomotion, helping animals maintain balance, timing, and efficient progression. It emerges from interactions among spinal central pattern-generating circuits, descending signals from the brain, and sensory feedback from muscles, joints, and skin; these pathways adjust the phase relationship between forelimb and hindlimb steps as speed or terrain changes. Studying this coordination reveals how distributed neural networks organize whole-body movement and adapt to changing demands. Neuroscience research uses it to investigate locomotor control, motor recovery after spinal cord injury, and strategies for restoring coordinated movement through rehabilitation or neuroprosthetic approaches.

Forelimb Hindlimb Coordination - Related Videos

Research

JoVE EoE - Rodent Models

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2023

In this video, we describe the footprint testing procedure and related analysis to assess gait and motor coordination in mice.

Methods for Acute and Subacute Murine Hindlimb Ischemia

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2016

Surgical induction of hindlimb ischemia in the mouse is useful to examine angiogenesis, however this is compromised in certain inbred mouse strains that display marked ischemia-induced tissue necrosis. Methods are described to induce subacute limb ischemia using ameroid constrictors to circumvent this problem through the induction of gradual arterial occlusion.

Education

JoVE Core - Chemistry

Coordination Number and Geometry

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2020

For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar. Coordination Number Molecular Geometry Example 2 linear [Ag(NH3)2]+ 3 trigonal planar [Cu(CN)3]2− 4 tetrahedral(d0 or d10), low oxidation...

Research

JoVE Journal - Neuroscience
Free Sample

A Novel Method for Assessing Proximal and Distal Forelimb Function in the Rat: the Irvine, Beatties and Bresnahan (IBB) Forelimb Scale

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Cited by 54 •

2010

Here we will describe a rodent behavioral assay that can detect recovery of both proximal and distal forelimb function including digit movements during a naturally occurring behavior that does not require extensive training or deprivation to enhance motivation.

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

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Cited by 19 •

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A paradigm is presented to analyze the acquisition of a high-precision skilled forelimb reaching task in rats.

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