Name: Klinik ortamlarda uyku bozukluğunu en aza indirmek için duvardan kan örnekleme yöntemi (Video) | JoVE Journal
Uploaded: 2025-06-13T14:00:00.000+00:00
Duration: 6 min 39 s
Description: Keşfedin, uyku bozukluğunu en aza indiren duvardan kan örnekleme yöntemiyle sirkadiyen ritim ve kardiyometabolik sağlık araştırmalarını. Bu teknik, 24 saat boyunca kesintisiz veri toplamayı sağlar.

ai_agent_IP

ai_agent

maintenance

instantTrialDurationMinutes

isBiopharma

enableNewMyJoveSectionDesign

educationFeatures

seoMetaApi

ai_copilot_institution_blacklist

ai_chat_institution_blacklist

freeAccessWindow

ssoRoleCapture

scheduledMaintenanceBanner

joveLabsFeatures

disable_autoplay_for_bots

extended_trial_duration

5 minutes

<ol><li>Cox, K. H., Takahashi, J. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Circadian+clock+genes+and+the+transcriptional+architecture+of+the+clock+mechanism%5BTitle%5D)+AND+%22J+Mol+Endocrinol%22%5BJournal%5D)">Circadian clock genes and the transcriptional architecture of the clock mechanism.</a> J Mol Endocrinol. 63 (4), R93-R102 (2019).</li>
<li>Broussard, J. L., et al. <a target="_blank" href="http://scholar.google.com/scholar?hl=en&safe=off&q=author%3aBroussard%2C+JL+%22Biological+Timekeeping%3A+Clocks%2C+Rhythms+and+Behaviour%22">Biological Timekeeping: Clocks, Rhythms and Behaviour</a>. , Springer. India. (2017).</li>
<li>Chellappa, S. L., Vujovic, N., Williams, J. S., Scheer, F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Impact+of+circadian+disruption+on+cardiovascular+function+and+disease%5BTitle%5D)+AND+%22Trends+Endocrinol+Metab%22%5BJournal%5D)">Impact of circadian disruption on cardiovascular function and disease.</a> Trends Endocrinol Metab. 30 (10), 767-779 (2019).</li>
<li>Broussard, J. L., Van Cauter, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Disturbances+of+sleep+and+circadian+rhythms%3A+novel+risk+factors+for+obesity%5BTitle%5D)+AND+%22Curr+Opin+Endocrinol+Diabetes+Obes%22%5BJournal%5D)">Disturbances of sleep and circadian rhythms: novel risk factors for obesity.</a> Curr Opin Endocrinol Diabetes Obes. 23 (5), 353-359 (2016).</li>
<li>Hanlon, E., Van Cauter, E. V., Tasali, E., Broussard, J. <a target="_blank" href="http://scholar.google.com/scholar?hl=en&safe=off&q=author%3aHanlon%2C+E+%22Endocrine+Physiology+in+Relation+to+Sleep+and+Sleep+Disturbances.+Principles+and+Pract+Sleep+Medicine%22">Endocrine Physiology in Relation to Sleep and Sleep Disturbances. Principles and Pract Sleep Medicine</a>. , Elsevier Saunders, MO. (2021).</li>
<li>Prasad, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+smartphone+intervention+to+promote+time+restricted+eating+reduces+body+weight+and+blood+pressure+in+adults+with+overweight+and+obesity%3A+a+pilot+study%5BTitle%5D)+AND+%22Nutrients%22%5BJournal%5D)">A smartphone intervention to promote time restricted eating reduces body weight and blood pressure in adults with overweight and obesity: a pilot study.</a> Nutrients. 13 (7), 2148(2021).</li>
<li>Procopio, S. B., Esser, K. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Clockwork+conditioning%3A+aligning+the+skeletal+muscle+clock+with+time-of-day+exercise+for+cardiometabolic+health%5BTitle%5D)+AND+%22J+Mol+Cell+Cardiol%22%5BJournal%5D)">Clockwork conditioning: aligning the skeletal muscle clock with time-of-day exercise for cardiometabolic health.</a> J Mol Cell Cardiol. 198, 36-44 (2025).</li>
<li>Holtman, S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Changes+in+circadian+timing+following+a+one-week+in-home+sleep+extension+manipulation+in+habitually+short-sleeping+adolescents%5BTitle%5D)+AND+%22Sleep%22%5BJournal%5D)">Changes in circadian timing following a one-week in-home sleep extension manipulation in habitually short-sleeping adolescents.</a> Sleep. 48 (2), zsae273(2024).</li>
<li>Chellappa, S. L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Daytime+eating+prevents+internal+circadian+misalignment+and+glucose+intolerance+in+night+work%5BTitle%5D)+AND+%22Sci+Adv%22%5BJournal%5D)">Daytime eating prevents internal circadian misalignment and glucose intolerance in night work.</a> Sci Adv. 7, eabg9910(2021).</li>
<li>Skene, D. J., Arendt, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Human+circadian+rhythms%3A+physiological+and+therapeutic+relevance+of+light+and+melatonin%5BTitle%5D)+AND+%22Ann+Clin+Biochem%22%5BJournal%5D)">Human circadian rhythms: physiological and therapeutic relevance of light and melatonin.</a> Ann Clin Biochem. 43 (Pt 5), 344-353 (2006).</li>
<li>Powell, D. J., Schlotz, W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Daily+life+stress+and+the+cortisol+awakening+response%3A+testing+the+anticipation+hypothesis%5BTitle%5D)+AND+%22PLoS+One%22%5BJournal%5D)">Daily life stress and the cortisol awakening response: testing the anticipation hypothesis.</a> PLoS One. 7 (12), e52067(2012).</li>
<li>Wright, K. P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Influence+of+sleep+deprivation+and+circadian+misalignment+on+cortisol%2C+inflammatory+markers%2C+and+cytokine+balance%5BTitle%5D)+AND+%22Brain+Behav+Immun%22%5BJournal%5D)">Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance.</a> Brain Behav Immun. 47, 24-34 (2015).</li>
<li>Ikegami, K., Refetoff, S., Van Cauter, E., Yoshimura, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Interconnection+between+circadian+clocks+and+thyroid+function%5BTitle%5D)+AND+%22Nat+Rev+Endocrinol%22%5BJournal%5D)">Interconnection between circadian clocks and thyroid function.</a> Nat Rev Endocrinol. 15 (10), 590-600 (2019).</li>
<li>Kessler, L., Nedeltcheva, A., Imperial, J., Penev, P. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Changes+in+serum+TSH+and+free+T4+during+human+sleep+restriction%5BTitle%5D)+AND+%22Sleep%22%5BJournal%5D)">Changes in serum TSH and free T4 during human sleep restriction.</a> Sleep. 33 (8), 1115-1118 (2010).</li>
<li>Van Cauter, E., Plat, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Physiology+of+growth+hormone+secretion+during+sleep%5BTitle%5D)+AND+%22J+Pediatr%22%5BJournal%5D)">Physiology of growth hormone secretion during sleep.</a> J Pediatr. 128 (5 Pt 2), S32-S37 (1996).</li>
<li>Morselli, L., Leproult, R., Balbo, M., Spiegel, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Role+of+sleep+duration+in+the+regulation+of+glucose+metabolism+and+appetite%5BTitle%5D)+AND+%22Best+Pract+Res+Clin+Endocrinol+Metab%22%5BJournal%5D)">Role of sleep duration in the regulation of glucose metabolism and appetite.</a> Best Pract Res Clin Endocrinol Metab. 24 (5), 687-702 (2010).</li>
<li>Kapcala, L. P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Twenty-four-hour+prolactin+secretory+patterns+in+women+with+galactorrhea%2C+normal+menses%2C+normal+random+prolactin+levels+and+abnormal+sellar+tomograms%5BTitle%5D)+AND+%22J+Endocrinol+Invest%22%5BJournal%5D)">Twenty-four-hour prolactin secretory patterns in women with galactorrhea, normal menses, normal random prolactin levels and abnormal sellar tomograms.</a> J Endocrinol Invest. 7 (5), 455-460 (1984).</li>
<li>Sassin, J. F., Frantz, A. G., Kapen, S., Weitzman, E. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+nocturnal+rise+of+human+prolactin+is+dependent+on+sleep%5BTitle%5D)+AND+%22J+Clin+Endocrinol+Metab%22%5BJournal%5D)">The nocturnal rise of human prolactin is dependent on sleep.</a> J Clin Endocrinol Metab. 37 (3), 436-440 (1973).</li>
<li>Chaput, J. -P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+role+of+insufficient+sleep+and+circadian+misalignment+in+obesity%5BTitle%5D)+AND+%22Nat+Rev+Endocrinol%22%5BJournal%5D)">The role of insufficient sleep and circadian misalignment in obesity.</a> Nat Rev Endocrinol. 19 (2), 82-97 (2023).</li>
<li>Broussard, J. L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Sleep+restriction+increases+free+fatty+acids+in+healthy+men%5BTitle%5D)+AND+%22Diabetologia%22%5BJournal%5D)">Sleep restriction increases free fatty acids in healthy men.</a> Diabetologia. 58 (4), 791-798 (2015).</li>
<li>Vaughn, L. K., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Endocannabinoid+signalling%3A+has+it+got+rhythm%5BTitle%5D)+AND+%22Br+J+Pharmacol%22%5BJournal%5D)">Endocannabinoid signalling: has it got rhythm.</a> Br J Pharmacol. 160 (3), 530-543 (2010).</li>
<li>Lindgren, O., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Differential+islet+and+incretin+hormone+responses+in+morning+versus+afternoon+after+standardized+meal+in+healthy+men%5BTitle%5D)+AND+%22J+Clin+Endocrinol+Metab%22%5BJournal%5D)">Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men.</a> J Clin Endocrinol Metab. 94 (8), 2887-2892 (2009).</li>
<li>Wesselius, H. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Quality+and+quantity+of+sleep+and+factors+associated+with+sleep+disturbance+in+hospitalized+patients%5BTitle%5D)+AND+%22JAMA+Intern+Med%22%5BJournal%5D)">Quality and quantity of sleep and factors associated with sleep disturbance in hospitalized patients.</a> JAMA Intern Med. 178 (9), 1201-1208 (2018).</li>
<li>Markwald, R. R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Impact+of+insufficient+sleep+on+total+daily+energy+expenditure%2C+food+intake%2C+and+weight+gain%5BTitle%5D)+AND+%22Proc+Natl+Acad+Sci+U+S+A%22%5BJournal%5D)">Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain.</a> Proc Natl Acad Sci U S A. 110 (14), 5695-5700 (2013).</li>
<li>McHill, A. W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Impact+of+circadian+misalignment+on+energy+metabolism+during+simulated+nightshift+work%5BTitle%5D)+AND+%22Proc+Natl+Acad+Sci+U+S+A%22%5BJournal%5D)">Impact of circadian misalignment on energy metabolism during simulated nightshift work.</a> Proc Natl Acad Sci U S A. 111 (48), 17302-17307 (2014).</li>
<li>Depner, C. M., Melanson, E. L., McHill, A. W., Wright, K. P. Jr <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mistimed+food+intake+and+sleep+alters+24-hour+time-of-day+patterns+of+the+human+plasma+proteome%5BTitle%5D)+AND+%22Proc+Natl+Acad+Sci+U+S+A%22%5BJournal%5D)">Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome.</a> Proc Natl Acad Sci U S A. 115 (23), E5390-E5399 (2018).</li>
<li>Mullington, J. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Sleep+loss+reduces+diurnal+rhythm+amplitude+of+leptin+in+healthy+men%5BTitle%5D)+AND+%22J+Neuroendocrinol%22%5BJournal%5D)">Sleep loss reduces diurnal rhythm amplitude of leptin in healthy men.</a> J Neuroendocrinol. 15 (9), 851-854 (2003).</li>
<li>Ona, E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+technique+for+improved+blood+sampling+during+sleep+studies%5BTitle%5D)+AND+%22Psychophysiology%22%5BJournal%5D)">A technique for improved blood sampling during sleep studies.</a> Psychophysiology. 31 (6), 609-610 (1994).</li>
<li>Schlierf, G., Dorow, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Diurnal+patterns+of+triglycerides%2C+free+fatty+acids%2C+blood+sugar%2C+and+insulin+during+carbohydrate-induction+in+man+and+their+modification+by+nocturnal+suppression+of+lipolysis%5BTitle%5D)+AND+%22J+Clin+Invest%22%5BJournal%5D)">Diurnal patterns of triglycerides, free fatty acids, blood sugar, and insulin during carbohydrate-induction in man and their modification by nocturnal suppression of lipolysis.</a> J Clin Invest. 52 (3), 732-740 (1973).</li>
<li>Schlierf, G., Reinheimer, W., Stossberg, V. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Diurnal+patterns+of+plasma+triglycerides+and+free+fatty+acids+in+normal+subjects+and+in+patients+with+endogenous+%28type+IV%29+hyperlipoproteinemia%5BTitle%5D)+AND+%22Nutr+Metab%22%5BJournal%5D)">Diurnal patterns of plasma triglycerides and free fatty acids in normal subjects and in patients with endogenous (type IV) hyperlipoproteinemia.</a> Nutr Metab. 13 (2), 80-91 (1971).</li>
<li>Swanson, C. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((turnover+markers+after+sleep+restriction+and+circadian+disruption%3A+a+mechanism+for+sleep-related+bone+loss+in+humans%5BTitle%5D)+AND+%22J+Clin+Endocrinol+Metab%22%5BJournal%5D)">turnover markers after sleep restriction and circadian disruption: a mechanism for sleep-related bone loss in humans.</a> J Clin Endocrinol Metab. 102 (10), 3722-3730 (2017).</li>
<li>Van Cauter, E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Modulation+of+glucose+regulation+and+insulin+secretion+by+circadian+rhythmicity+and+sleep%5BTitle%5D)+AND+%22J+Clin+Invest%22%5BJournal%5D)">Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep.</a> J Clin Invest. 88 (3), 934-942 (1991).</li>
<li>Rynders, C. A., Morton, S. J., Bessesen, D. H., Wright, K. P. Jr, Broussard, J. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Circadian+rhythm+of+substrate+oxidation+and+hormonal+regulators+of+energy+balance%5BTitle%5D)+AND+%22Obesity+%28Silver+Spring%29%22%5BJournal%5D)">Circadian rhythm of substrate oxidation and hormonal regulators of energy balance.</a> Obesity (Silver Spring). 28 (Suppl 1), S104-S113 (2020).</li>
<li>Thosar, S. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Circadian+rhythm+of+vascular+function+in+midlife+adults%5BTitle%5D)+AND+%22Arterioscler+Thromb+Vasc+Biol%22%5BJournal%5D)">Circadian rhythm of vascular function in midlife adults.</a> Arterioscler Thromb Vasc Biol. 39 (6), 1203-1211 (2019).</li>
<li>Thosar, S. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Morning+impairment+in+vascular+function+is+unrelated+to+overnight+sleep+or+the+inactivity+that+accompanies+sleep%5BTitle%5D)+AND+%22Am+J+Physiol+Regul+Integr+Comp+Physiol%22%5BJournal%5D)">Morning impairment in vascular function is unrelated to overnight sleep or the inactivity that accompanies sleep.</a> Am J Physiol Regul Integr Comp Physiol. 315 (5), R986-R993 (2018).</li>
<li>Dimsdale, J. E., Coy, T., Ziegler, M. G., Ancoli-Israel, S., Clausen, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+effect+of+sleep+apnea+on+plasma+and+urinary+catecholamines%5BTitle%5D)+AND+%22Sleep%22%5BJournal%5D)">The effect of sleep apnea on plasma and urinary catecholamines.</a> Sleep. 18 (5), 377-381 (1995).</li>
<li>Klerman, E. B., Gershengorn, H. B., Duffy, J. F., Kronauer, R. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Comparisons+of+the+variability+of+three+markers+of+the+human+circadian+pacemaker%5BTitle%5D)+AND+%22J+Biol+Rhythms%22%5BJournal%5D)">Comparisons of the variability of three markers of the human circadian pacemaker.</a> J Biol Rhythms. 17 (2), 181-193 (2002).</li>
<li>Benloucif, S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Measuring+melatonin+in+humans%5BTitle%5D)+AND+%22J+Clin+Sleep+Med%22%5BJournal%5D)">Measuring melatonin in humans.</a> J Clin Sleep Med. 4 (1), 66-69 (2008).</li>
<li>Lammers, W. J., Badia, P., Hughes, R., Harsh, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Temperature%2C+time-of-night+of+testing%2C+and+responsiveness+to+stimuli+presented+while+sleeping%5BTitle%5D)+AND+%22Psychophysiology%22%5BJournal%5D)">Temperature, time-of-night of testing, and responsiveness to stimuli presented while sleeping.</a> Psychophysiology. 28 (4), 463-467 (1991).</li>
<li>Alikhan, R., Forster, R., Cohen, A. T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Heparin+for+the+prevention+of+venous+thromboembolism+in+acutely+ill+medical+patients+%28excluding+stroke+and+myocardial+infarction%29%5BTitle%5D)+AND+%22Cochrane+Database+Syst+Rev%22%5BJournal%5D)">Heparin for the prevention of venous thromboembolism in acutely ill medical patients (excluding stroke and myocardial infarction).</a> Cochrane Database Syst Rev. 2014 (5), CD003747(2014).</li>
<li>Roth, B., Ekelund, M., Fan, B. G., Ekstrom, U., Nilsson-Ehle, P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effects+of+heparin+and+low+molecular+weight+heparin+on+lipid+transport+during+parenteral+feeding+in+the+rat%5BTitle%5D)+AND+%22Acta+Anaesthesiol+Scand%22%5BJournal%5D)">Effects of heparin and low molecular weight heparin on lipid transport during parenteral feeding in the rat.</a> Acta Anaesthesiol Scand. 40 (1), 102-111 (1996).</li>
<li>Weintraub, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Continuous+intravenous+heparin+administration+in+humans+causes+a+decrease+in+serum+lipolytic+activity+and+accumulation+of+chylomicrons+in+circulation%5BTitle%5D)+AND+%22J+Lipid+Res%22%5BJournal%5D)">Continuous intravenous heparin administration in humans causes a decrease in serum lipolytic activity and accumulation of chylomicrons in circulation.</a> J Lipid Res. 35 (2), 229-238 (1994).</li>
<li>Schallom, M. E., Prentice, D., Sona, C., Micek, S. T., Skrupky, L. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Heparin+or+0.9%25+sodium+chloride+to+maintain+central+venous+catheter+patency%3A+a+randomized+trial%5BTitle%5D)+AND+%22Crit+Care+Med%22%5BJournal%5D)">Heparin or 0.9% sodium chloride to maintain central venous catheter patency: a randomized trial.</a> Crit Care Med. 40 (6), 1820-1826 (2012).</li>
<li>Rahman, S. A., Wright, K. P. Jr, Lockley, S. W., Czeisler, C. A., Gronfier, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Characterizing+the+temporal+dynamics+of+melatonin+and+cortisol+changes+in+response+to+nocturnal+light+exposure%5BTitle%5D)+AND+%22Sci+Rep%22%5BJournal%5D)">Characterizing the temporal dynamics of melatonin and cortisol changes in response to nocturnal light exposure.</a> Sci Rep. 9 (1), 19720(2019).</li>
</ol>

<table><tbody><tr><td>1 mL astarlama hacmi ile 9-inç standart delikli IV uzatma seti, çıkarılabilir SmartSite iğnesiz konnektör, sürgülü kelepçe ve spinli erkek luer kilidi</td><td>Medline</td><td>IME22059EH</td><td></td></tr><tr><td>%0,9 Sodyum Klorür enjeksiyonu USP 10 mL 10 mL bir şırıngada ZR</td><td>Excelsior Medical</td><td>EMZE010001</td><td></td></tr><tr><td>Alkol hazırlık pedi</td><td>Medline</td><td>MDS090737</td><td></td></tr><tr><td>BD Insyte Autoguard Kanatlı 20 G kateter</td><td>Medline</td><td>381534</td><td></td></tr><tr><td>BD Plastipak 3 mL şırınga</td><td>Fischer Scientific</td><td>309657</td><td></td></tr><tr><td>CoFlexNL</td><td>Medline</td><td>5200CP</td><td></td></tr><tr><td>IV uzatma seti 192 inç, küçük borulu</td><td>Yoğun Bakım Tıp</td><td>B2202</td><td>Malzeme siparişi vermek için ICU Medical ile hesap açmak gereklidir</td></tr><tr><td>Dokunmamış gazlı bez süngerleri</td><td>Medline</td><td>NON25223</td><td></td></tr><tr><td>Tegaderm</td><td>Medline</td><td>1624W</td><td></td></tr><tr><td>Ultra(TM) 3 stockcockw/döner erkek luer kilidi</td><td>Medline</td><td>MX2311L</td><td></td></tr></tbody></table>

klinik ortamlarda uyku bozukluğunu en aza indirmek için duvardan kan örnekleme yöntemi

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

Klinik ortamlarda uyku bozukluğunu en aza indirmek için duvardan kan örnekleme yöntemi

Physiological rhythms, including diurnal and circadian rhythms, play a critical role in health, with disturbances increasingly linked to cardiovascular ...

through-wall-blood-sampling-method-to-minimize-sleep-disruption

Research

JoVE Journal

Medicine

Tıp

Sıçanlarda kan damarlarının Kronik kateterizasyon sık sık bir süre üzerinden veya direkt bilinçli bir kan basıncı ölçümü için kan örneği almak, maddelerin yönetimi için gereklidir. Sıçan ve ilgili bilinçli hayvan kan basıncı ölçümleri Femoral arteriyel kateterizasyon gösterilmelidir.

Kan Örnekleme, İlaç İdaresi ve Bilinçli Kan Basıncı ve Nabız ölçümleri Femoral Arter ve Venöz Kateterizasyon

Daha fazla analiz için çeşitli bileşenler elde etmek üzere tam kanın işlenmesi için bir metodolojinin ana hatlarını çiziyoruz. Klinik olmayan bir ortamda tam kan örneklerinin hızlı, yüksek verimli eş zamanlı işlenmesini sağlayan kolaylaştırılmış bir protokolü optimize ettik.

Topluluk tabanlı Ayar Elde Edilen Örneklerin hızlı Fraksiyonlama ve Tam Kan Bileşenlerinin İzolasyonu

Burada, ev uyku yönergeleri ile yapılandırılmış bir katılımcı ziyaret geliştirmek için bir yöntemi sağlayarak sınama veri kalitesini artırmak için bir protokol mevcut. Bu iletişim kuralı bir adım adım eğitim kılavuzu ile fotoğraf ekipman uygun yerleşim sağlamak için birlikte uygulanmasını içerir.

Büyük erişkinlerde izleme multi-modal ev uyku

Uyku kaybı ve sirkadiyen hizalama çok sayıda operasyonel kazalara ve olaylara katkıda bulunur. Tedbirlerin ve çalışma çizelgeleme tasarımlarının etkinliğini azaltmaya yönelik etkinliği, operasyonel ortamlarda değerlendirmek zor olabilir. Bu yazıda karmaşık operasyonel ortamlarda uyku, sirkadiyen, yorgunluk ve performans verilerinin toplanması için bir yaklaşım özetlenmiştir.

Karmaşık operasyonel ortamlarda uyku, Circadian, yorgunluk ve performans verilerini toplama

Burada, katılımcıların Münih ChronoType Anketi, altın standart sirkadiyen faz biyobelirteçleri ve aktigrafik ölçüleri temel alınarak sirkadiyen fenotip gruplarına doğru kategorize etmesini takiben performanstaki diurnal ritimleri araştırmak için bir yöntem saklıyız.

Gerçek Dünyada İnsan Sirkadiyen Fenotilik ve Diurnal Performans Testi

Mevcut protokol, sıçanlarda subklaviyen damardan kan toplamak için basit ve etkili bir yöntemi açıklamaktadır. Anestezi olmadan hızlı, zamanında ve kolayca tanımlanabilir örnekleme sağlar ve tekrarlayan numune toplama yoluyla yüksek kaliteli kan elde eder.

Bilinçli Sıçan Subklaviyen Veninden Tekrarlayan Kan Örneklemesi

Mevcut protokol, mikrodiyaliz tekniğini kullanarak sıçan kalp kanının gerçek zamanlı ve dinamik olarak toplanması için basit ve etkili bir yöntemi tanımlamaktadır.

Noninvaziv Mikrodiyaliz Tekniği ile Sıçan Kalbinden Dinamik Sürekli Kan Ekstraksiyonu

Protokol, sürekli video-elektroensefalogram (EEG) monitörizasyonuna paralel olarak gerçekleştirilen epileptik sıçanlardan tekrarlanan beyin omurilik sıvısı ve kan alımlarını gösterir. Bunlar, çeşitli vücut sıvısı moleküllerindeki değişiklikler ile nöbet aktivitesi arasındaki olası bağlantıları araştırmak için etkilidir.

EEG Kayıtları Sırasında Sıçanlarda Lateral Kuyruk Veninden Beyin Omurilik Sıvısı ve Kan Örneği Alınması

Luteinize edici hormon (LH) pulsatilitesi, üreme fonksiyonunun ayırt edici özelliğidir. Seri otomatik kan alımına bağlı belirli nöronal popülasyonların uzaktan aktivasyonu için bir protokol açıklıyoruz. Bu teknik, bilinçli serbest hareket eden ve rahatsız edilmemiş hayvanlarda zamanlanmış hormonal modülasyona, çoğullamaya ve LH seviyeleri üzerindeki manipülasyon etkilerini en aza indirmeye izin verir.

Farelerde Dolaşımdaki Luteinize Edici Hormonu İndüklemek ve Ölçmek için Otomatik Kan Örneklemesi ile Birleştirilmiş Uzaktan Nöronal Aktivasyon

Burada, sıçanlarda anestezi olmadan hızlı, güvenli ve tekrarlanan kan alımını sağlayan etkili sıçan kısıtlaması ve subklavyen ven ponksiyon yöntemlerinin bir kombinasyonunu sunuyoruz.

Bilinçli Sıçanlarda Subklavyen Ven Kan Örneklemesi

Keşfedin, uyku bozukluğunu en aza indiren duvardan kan örnekleme yöntemiyle sirkadiyen ritim ve kardiyometabolik sağlık araştırmalarını. Bu teknik, 24 saat boyunca kesintisiz veri toplamayı sağlar.

Klinik ortamlarda uyku bozukluğunu en aza indirmek için duvardan kan örnekleme yöntemi

Daha fazla video keşfet