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JoVE Journal
Immunology and Infection

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Examination of the Telomere G-overhang Structure in Trypanosoma brucei
 

Examination of the Telomere G-overhang Structure in Trypanosoma brucei

Article doi: 10.3791/1959
January 26th, 2011

Summary January 26th, 2011

Telomeres are essential for chromosome stability and the telomere G-overhang structure is essential for telomerase-mediated telomere maintenance. We have recently adopted two methods for detecting the telomere G-overhang structure in Trypanosoma brucei, which are native in-gel hybridization and ligation-mediated primer extension, which will be described.

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