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JoVE Journal
Biology

This content is Open Access.

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
 

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Article doi: 10.3791/2260
October 16th, 2010

Summary October 16th, 2010

Our protocol describes how to dissect the rat abdominal mammary gland and how to prepare mammary gland whole mounts. It also describes how to analyze mammary gland morphology using three end-points (number of terminal end buds, epithelial elongation and differentiation) and to use these results to predict mammary cancer risk in rats which were exposed to dietary modifications in utero or during prepuberty.

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